Objective
Dopamine neurons play a central role in major illnesses, such as anxiety and mood disorders, schizophrenia, autism-spectrum disorders, Parkinson’s disease, epilepsy, and dementia. A multidisciplinary approach must be taken by European researchers to discover the molecular basis of dopamine neurodegeneration and how new technologies will lead to repair and regeneration of neuronal systems in the brain. The TINTIN proposal describes how early stage researchers (ESRs) and experienced researchers (ERs) will undertake advanced research training projects on metabolism and autophagy in neurons, induced pluripotent stem cells and neurorepair systems. Parallel research projects will involve computational modelling of metabolism in the dopamine neuron and the in silico design of novel therapeutics that are selectively transported into the dopamine neuron. This fundamental training and research will be merged with new cutting edge glycan based biomarker technologies, drug simulation and computational/mathematical models of dopaminergic neurons. TINTIN will train young researchers by merging key research groups in 7 Universities and 8 industry/SME partners from Western Europe (Ireland, UK) across central and Southern Europe (Denmark, Germany, Austria, Italy, Spain) and Eastern Europe (Turkey). The secondments of ESRs and ERs into and out of 8 commercial partners in the area of glycan discovery and drug design will ensure that researchers receive intensive training in emerging research areas in neurotherapeutic development as well as key information in how to commercialize such innovation and discovery. The breadth of the aims, techniques and knowledge of TINTIN, the academic basis, the integrating of ESRs and ERs into industry, the potential for transfer to the European pharmaceutical industry, and enrichment of scientific training across Europe all fit the ITN model.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
- medical and health sciences basic medicine neurology epilepsy
- medical and health sciences basic medicine medicinal chemistry
- medical and health sciences medical biotechnology cells technologies stem cells
- medical and health sciences basic medicine neurology dementia
- medical and health sciences clinical medicine psychiatry schizophrenia
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP7-PEOPLE-2013-ITN
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
D02 CX56 Dublin
Ireland
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.