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Content archived on 2024-06-18

Powering cells with light: the synthetic biology of photosynthesis

Objective

Billions of tonnes of chlorophylls are synthesised every year, then incorporated into the photosynthetic complexes that harvest and trap the solar energy that powers the biosphere. An understanding of the mechanisms that deliver chlorophylls to the growing photosynthetic apparatus is important for fundamental reasons, and also for future exploitation of photosynthesis as an energy source.

The SYNTHPHOTO project comprises two interlinked sections: the first (SP1) will provide a step change in our knowledge of photosystem assembly by showing how newly-synthesised pigments emerging from the (bacterio)chlorophyll synthases encounter the membrane-embedded assembly machinery and form the growing photosynthetic unit. Innovations in atomic force microscopy will provide the first nanoscale mapping information on the membrane location of the assembly machinery, and state-of-the-art mass spectrometry will quantify every component in the assembly pathway.

SP2 will harness this knowledge for the design and construction of new biological and bioinspired light-gathering and energy-trapping systems. The synthetic biology approach of SP2 will splice genes for pigment and assembly pathways from a variety of bacteria, reconfiguring the photosynthetic apparatus for enhanced spectral coverage. SP2 will explore the potential for ‘bottom-up’ redesign and in vivo production of tailored arrays of photosynthetic complexes and enzymes. Building hybrid photosystems in SP2 augments the aims of SP1 by testing the adaptability of the native biosynthetic machinery, providing a new level of understanding of pigment biosynthesis and photosystem assembly pathways.

The overall aim of SYNTHPHOTO is to discover the mechanisms of assembly of the bacterial photosynthetic apparatus, and to harness this understanding for the design, development and implementation of new biological and bioinspired light-gathering and energy trapping systems.

Fields of science (EuroSciVoc)

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Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

ERC-2013-ADG
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Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

ERC-AG - ERC Advanced Grant

Host institution

THE UNIVERSITY OF SHEFFIELD
EU contribution
€ 2 484 955,00
Address
FIRTH COURT WESTERN BANK
S10 2TN Sheffield
United Kingdom

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Region
Yorkshire and the Humber South Yorkshire Sheffield
Activity type
Higher or Secondary Education Establishments
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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

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Beneficiaries (1)

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