Objective
Fungal plant pathogens are major and rising threats for global food security and environment sustainability. Necrotrophic fungi, that kill host cells for infection, are among the most devastating plant pathogens, yet our knowledge on the molecular bases of plant interaction with necrotrophs is one of the least advanced in the field of plant pathology. The lack of appropriate genetic resources and accurate high-throughput methods has prevented holistic approaches of quantitative immunity to necrotrophs.
We recently documented extensive variation in the response to the necrotrophic White Mold fungus Sclerotinia sclerotiorum in natural populations of Arabidopsis thaliana, a model organism for plant biology. Using the latest developments in comparative genomics, our work over the last years has significantly improved our understanding of the emergence of virulence in filamentous plant pathogens. In this project, we will take advantage of this dual expertise on plants and pathogens to propose converging innovative approaches initiated from each partner of the interaction to provide the most complete characterization of plant quantitative immunity to necrotrophs. We will use a unique combination of genome-wide association genetics and comparative patho-genomics to dissect the components mediating quantitative immunity to necrotrophs, study their contribution to the evolution of resistance and their interplay with other stress responses. The selected pathosystem will also allow to rapidly exploit this knowledge to develop innovative approaches for breeding crop plants resistant to the White Mold disease.
Through this multi-disciplinary research program, combining cutting-edge genome wide association mapping, comparative genomics, reverse genetics, ecogenomics, cell biology and biochemistry we will greatly advance our understanding of the mechanisms underlying plant immunity and demonstrate the impact of this knowledge on resistance breeding.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences biochemistry
- natural sciences biological sciences cell biology
- natural sciences biological sciences microbiology mycology
- medical and health sciences health sciences nutrition
- natural sciences biological sciences genetics genomes
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
ERC-2013-StG
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Host institution
75007 PARIS CEDEX 07
France
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.