Forschungs- & Entwicklungsinformationsdienst der Gemeinschaft - CORDIS

FP7 OraMod logo

OraMod

Project reference: 611425
Funded under

VPH based predictive model for oral cancer reoccurrence in the clinical practice

From 2013-10-01 to 2016-09-30

Project details

Total cost:

EUR 4 154 114

EU contribution:

EUR 3 098 000

Coordinated in:

Italy

Call for proposal:

FP7-ICT-2013-10See other projects for this call

Funding scheme:

CP - Collaborative project (generic)

OraMod project: Helping clinicians predict oral cavity cancer reoccurrence

Genomic markers and computer models can predict the reoccurance of oral cavity cancer. But these innovative diagnostic technologies are currently stuck in labs and are not being used by clinicians in hospitals. The EU-funded project OraMod, led by the University of Parma, aims to solve this problem by building an IT platform and a diagnostic device.

Objective

Clinical oncology is undergoing a profound transformation, driven by the availability of new diagnostic technologies, novel techniques for bio-molecular and genomic tests aimed at predictive markers discovery, smart mathematical and statistical algorithms for disease modelling and prediction simulation, powerful computing for data mining and data analysis on large datasets of heterogeneous data. The approach to care delivery is also shifting from treatment administration to treatment planning, supported by predictive modelling. OraMod perfectly fits in this scenario: the project converges the technology and scientific breakthrough from research into clinical practice by developing a novel, modular and integrated ICT environment aimed at supporting key aspects of the clinical management of oral cavity cancer patients. OraMod focuses on the integration of data, medical knowledge, multi-disciplinary collaborative best clinical practices and cutting-edge technologies, including modelling, in-silico simulation, and decision support aimed at early and precisely predict oral cancer reoccurrence. In so doing the project addresses urgent clinical and societal needs: better clinical decisions regarding treatment and follow-up, reduced costs, and benefits for patients from reduced post-treatment morbidity. Building from previous ICT-224483 NeoMark, OraMod will combine a predictive model relying on a variety of data collected and managed in the system repository, with decision support and in-silico simulation tools, an interactive Knowledge Assisted Visualization in line with the "Digital Patient" paradigm, a collaborative working space to support multi-disciplinary decision-making, a sophisticated suite for diagnostic image analysis and features extraction and a qRT-PCR device and lab-on-chip for fast, precise, quantitative detection of the genomic markers included in the model. A clinical trial in four European pilot hospitals will demonstrate tangible clinical benefits.

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Coordinator

UNIVERSITA DEGLI STUDI DI PARMA
Italy

EU contribution: EUR 519 400


VIA GRAMSCI 14
43100 PARMA
Italy
Administrative contact: Tito Poli
Tel.: +39 0521703109
Fax: +39 0521703080
E-mail

Participants

HEINRICH-HEINE-UNIVERSITAET DUESSELDORF
Germany

EU contribution: EUR 304 562


UNIVERSITAETSSTRASSE 1
40225 DUSSELDORF
Germany
Administrative contact: Doris Neubert
Tel.: +49 0211 81 19586
Fax: +49 0211 81 18576
E-mail
FRAUNHOFER GESELLSCHAFT ZUR FORDERUNG DER ANGEWANDTEN FORSCHUNG EV
Germany

EU contribution: EUR 309 254


HANSASTRASSE 27C
80686 MUNCHEN
Germany
Administrative contact: Christoph Schulte
Tel.: +49 89 1205 2728
Fax: +49 89 1205 7534
E-mail
Teknologian tutkimuskeskus VTT Oy
Finland

EU contribution: EUR 165 699


VUORIMIEHENTIE 3
02150 Espoo
Finland
Administrative contact: Jaana Heino
Tel.: +358 20 722 3301
Fax: +358 20 722 3499
E-mail
TEKNOLOGIAN TUTKIMUSKESKUS VTT
Participation ended
Finland

EU contribution: EUR 60 856


TEKNIIKANTIE 4 A
02044 VTT ESPOO
Finland
Administrative contact: Jaana Heino
Tel.: +358 20 722 3301
Fax: +358 20 722 3499
E-mail
VCI ANONYMOS ETAIREIA KAINOTOMON LYSEON PLIROFORIKIS
Greece

EU contribution: EUR 264 000


CHEIMARAS 5
15125 MAROUSSI ATHINA
Greece
Administrative contact: Giannis Katsaros
Tel.: +30 2130186942
Fax: +302130186888
E-mail
STMICROELECTRONICS SRL
Italy

EU contribution: EUR 181 125


VIA C.OLIVETTI 2
20864 AGRATE BRIANZA
Italy
Administrative contact: Sara Loi
Tel.: +390396037685
E-mail
ONETONET S.R.L.
Italy

EU contribution: EUR 384 604


VIA VALTELLINA 16
20159 MILANO
Italy
Administrative contact: Augusto Ruggeri
Tel.: +39 0236587365
Fax: +39 02 36587910
E-mail
STICHTING VU-VUMC
Netherlands

EU contribution: EUR 908 500


DE BOELELAAN 1105
1081 HV AMSTERDAM
Netherlands
Administrative contact: Michel Telkamp
Tel.: +31204448190
Fax: +31204448260
E-mail
Record Number: 110909 / Last updated on: 2016-04-11