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OraMod

Project ID: 611425
Funded under

VPH based predictive model for oral cancer reoccurrence in the clinical practice

From 2013-10-01 to 2016-09-30, closed project | OraMod Website

Project details

Total cost:

EUR 4 153 734

EU contribution:

EUR 3 098 000

Coordinated in:

Italy

Call for proposal:

FP7-ICT-2013-10See other projects for this call

Funding scheme:

CP - Collaborative project (generic)

Description

OraMod project: Helping clinicians predict oral cavity cancer reoccurrence

Genomic markers and computer models can predict the reoccurance of oral cavity cancer. But these innovative diagnostic technologies are currently stuck in labs and are not being used by clinicians in hospitals. The EU-funded project OraMod, led by the University of Parma, aims to solve this problem by building an IT platform and a diagnostic device.

Objective

Clinical oncology is undergoing a profound transformation, driven by the availability of new diagnostic technologies, novel techniques for bio-molecular and genomic tests aimed at predictive markers discovery, smart mathematical and statistical algorithms for disease modelling and prediction simulation, powerful computing for data mining and data analysis on large datasets of heterogeneous data. The approach to care delivery is also shifting from treatment administration to treatment planning, supported by predictive modelling. OraMod perfectly fits in this scenario: the project converges the technology and scientific breakthrough from research into clinical practice by developing a novel, modular and integrated ICT environment aimed at supporting key aspects of the clinical management of oral cavity cancer patients. OraMod focuses on the integration of data, medical knowledge, multi-disciplinary collaborative best clinical practices and cutting-edge technologies, including modelling, in-silico simulation, and decision support aimed at early and precisely predict oral cancer reoccurrence. In so doing the project addresses urgent clinical and societal needs: better clinical decisions regarding treatment and follow-up, reduced costs, and benefits for patients from reduced post-treatment morbidity. Building from previous ICT-224483 NeoMark, OraMod will combine a predictive model relying on a variety of data collected and managed in the system repository, with decision support and in-silico simulation tools, an interactive Knowledge Assisted Visualization in line with the "Digital Patient" paradigm, a collaborative working space to support multi-disciplinary decision-making, a sophisticated suite for diagnostic image analysis and features extraction and a qRT-PCR device and lab-on-chip for fast, precise, quantitative detection of the genomic markers included in the model. A clinical trial in four European pilot hospitals will demonstrate tangible clinical benefits.

Coordinator

UNIVERSITA DEGLI STUDI DI PARMA
Italy

EU contribution: EUR 519 400


VIA UNIVERSITA 12
43100 PARMA
Italy
Activity type: Higher or Secondary Education Establishments
Administrative contact: Tito Poli
Tel.: +39 0521703109
Fax: +39 0521703080

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Participants

FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.
Germany

EU contribution: EUR 309 254


HANSASTRASSE 27C
80686 MUNCHEN
Germany
Activity type: Research Organisations
Administrative contact: Christoph Schulte
Tel.: +49 89 1205 2728
Fax: +49 89 1205 7534

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HEINRICH-HEINE-UNIVERSITAET DUESSELDORF
Germany

EU contribution: EUR 304 562


UNIVERSITAETSSTRASSE 1
40225 DUSSELDORF
Germany
Activity type: Higher or Secondary Education Establishments
Administrative contact: Doris Neubert
Tel.: +49 0211 81 19586
Fax: +49 0211 81 18576

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Teknologian tutkimuskeskus VTT Oy
Finland

EU contribution: EUR 165 699


VUORIMIEHENTIE 3
02150 Espoo
Finland
Activity type: Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
Administrative contact: Jaana Heino
Tel.: +358 20 722 3301
Fax: +358 20 722 3499

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TEKNOLOGIAN TUTKIMUSKESKUS VTT
Participation ended
Finland

EU contribution: EUR 60 856


TEKNIIKANTIE 4 A
02044 ESPOO
Finland
Activity type: Other
Administrative contact: Jaana Heino
Tel.: +358 20 722 3301
Fax: +358 20 722 3499

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VCI ANONYMOS ETAIREIA KAINOTOMON LYSEON PLIROFORIKIS
Greece

EU contribution: EUR 264 000


CHEIMARAS 5
15125 MAROUSSI ATHINA
Greece
Activity type: Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative contact: Giannis Katsaros
Tel.: +30 2130186942
Fax: +302130186888

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ONETONET SRL
Italy

EU contribution: EUR 384 604


VIALE ORTLES 54/A
20139 MILANO MI
Italy
Activity type: Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative contact: Augusto Ruggeri
Tel.: +39 0236587365
Fax: +39 02 36587910

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STMICROELECTRONICS SRL
Italy

EU contribution: EUR 181 125


VIA C.OLIVETTI 2
20864 AGRATE BRIANZA
Italy
Activity type: Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative contact: Sara Loi
Tel.: +390396037685

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STICHTING VU
Participation ended
Netherlands

EU contribution: EUR 0


DE BOELELAAN 1105
1081 AMSTERDAM
Netherlands
Activity type: Higher or Secondary Education Establishments
Administrative contact: Michel Telkamp
Tel.: +31204448190
Fax: +31204448260

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STICHTING VUMC
Netherlands

EU contribution: EUR 908 500


DE BOELELAAN 1117
1081 AMSTERDAM
Netherlands
Activity type: Higher or Secondary Education Establishments
Administrative contact: Cedric van der Meulen
Tel.: +31 20 444 4876

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