Objetivo The global chemical industry is transitioning from petrochemical production processes to bio-based production processes. This transition creates a clear market need for technologies that reduce the development time and cost of cell factories. PROMYS will develop, validate and implement a novel synthetic biology platform technology termed ligand responsive regulation and selection systems. Ligand responsive regulation and selection systems are biological devices that integrate biological sensing modules, within larger regulatory networks to control cellular programs. This technology will drastically accelerate the construction, optimization and performance of cell factories by enabling industrial users to impose non-natural objectives on the engineered cell factory. PROMYS will address three major challenges in metabolic engineering that limit the development of new cell factories:1) Synthetic pathway construction2) Cell factory optimization3) Control of populations during fermentationLigand responsive regulation and selection systems will directly couple the presence of a desired chemical product or flux state within a cell, to the survival of the cell. As such, they allow the in vivo identification of the needle (e.g. functional pathway or optimized cell factories) in a haystack (e.g. large libraries). In addition, the technology developed in PROMYS will be applied to deliver increased fermentation yields by continuously selecting for high yielding cell factories within the fermentation population.PROMYS is industry driven and designed such that the expected innovations of each work package have a direct commercialization partner, which is willing to commit the necessary resources to develop commercial products from the innovation. Ámbito científico engineering and technologyindustrial biotechnologymetabolic engineeringnatural sciencesbiological sciencessynthetic biologyengineering and technologyindustrial biotechnologybioprocessing technologiesfermentation Programa(s) FP7-KBBE - Specific Programme "Cooperation": Food, Agriculture and Biotechnology Tema(s) KBBE.2013.3.6-02 - Synthetic Biology towards applications Convocatoria de propuestas FP7-KBBE-2013-7-single-stage Consulte otros proyectos de esta convocatoria Régimen de financiación CP-TP - Collaborative Project targeted to a special group (such as SMEs) Coordinador DANMARKS TEKNISKE UNIVERSITET Aportación de la UE € 2 312 890,00 Dirección ANKER ENGELUNDS VEJ 101 2800 Kongens Lyngby Dinamarca Ver en el mapa Región Danmark Hovedstaden Københavns omegn Tipo de actividad Higher or Secondary Education Establishments Contacto administrativo Birte Rasmussen Enlaces Contactar con la organización Opens in new window Sitio web Opens in new window Coste total Sin datos Participantes (6) Ordenar alfabéticamente Ordenar por aportación de la UE Ampliar todo Contraer todo BACMINE SL España Aportación de la UE € 813 471,00 Dirección CALLE ISAAC NEWTON 2 PARQUE 28760 TRES CANTOS Ver en el mapa Región Comunidad de Madrid Comunidad de Madrid Madrid Tipo de actividad Private for-profit entities (excluding Higher or Secondary Education Establishments) Contacto administrativo Pablo Pomposiello Miravent (Dr.) Enlaces Contactar con la organización Opens in new window Coste total Sin datos TECHNISCHE UNIVERSITAT DARMSTADT Alemania Aportación de la UE € 904 418,00 Dirección KAROLINENPLATZ 5 64289 Darmstadt Ver en el mapa Región Hessen Darmstadt Darmstadt, Kreisfreie Stadt Tipo de actividad Higher or Secondary Education Establishments Contacto administrativo Melanie Meermann-Zimmermann (Dr.) Enlaces Contactar con la organización Opens in new window Sitio web Opens in new window Coste total Sin datos RIJKSUNIVERSITEIT GRONINGEN Países Bajos Aportación de la UE € 1 004 400,00 Dirección Broerstraat 5 9712CP Groningen Ver en el mapa Región Noord-Nederland Groningen Overig Groningen Tipo de actividad Higher or Secondary Education Establishments Contacto administrativo Dick Veldhuis (Dr.) Enlaces Contactar con la organización Opens in new window Sitio web Opens in new window Coste total Sin datos THE UNIVERSITY OF WARWICK Reino Unido Aportación de la UE € 722 423,00 Dirección Kirby Corner Road - University House CV4 8UW Coventry Ver en el mapa Región West Midlands (England) West Midlands Coventry Tipo de actividad Higher or Secondary Education Establishments Contacto administrativo Peter Hedges (Dr.) Enlaces Contactar con la organización Opens in new window Sitio web Opens in new window Coste total Sin datos EVOLVA AG Suiza Aportación de la UE € 712 800,00 Dirección DUGGINGERSTRASSE 23 4153 Reinach Ver en el mapa Región Schweiz/Suisse/Svizzera Nordwestschweiz Basel-Landschaft Tipo de actividad Private for-profit entities (excluding Higher or Secondary Education Establishments) Contacto administrativo Michael Naesby (Mr.) Enlaces Contactar con la organización Opens in new window Sitio web Opens in new window Coste total Sin datos BIOSYNTIA APS Dinamarca Aportación de la UE € 718 000,00 Dirección KOGLE ALLE 6 2970 Horsholm Ver en el mapa Región Danmark Hovedstaden Nordsjælland Tipo de actividad Private for-profit entities (excluding Higher or Secondary Education Establishments) Contacto administrativo Andreas Laustsen (Mr.) Enlaces Contactar con la organización Opens in new window Sitio web Opens in new window Coste total Sin datos