ASSET (Action plan in Science in Society in Epidemics and Total pandemics) is a 48 month Mobilisation and Mutual Learning Action Plan (MMLAP), which aims to 1) forge a partnership with complementary perspectives, knowledge and experiences to address effectively scientific and societal challenges raised by pandemics and associated crisis management; 2) explore and map SiS-related issues in global pandemics; 3) define and test a participatory and inclusive strategy to succeed; 4) identify necessary resources to make sustainable the action after the project completion. ASSET combines public health, vaccine and epidemiological research, social and political sciences, law and ethics, gender studies, science communication and media, in order to develop an integrated, transdisciplinary, strategy, which will take place at different stages of the research cycle, combining local, regional and national levels.