Objective
One of the main challenges of 21st century biology is to describe the many factors controlling our genes – our ‘epigenetics’. Having sequenced the human genome in 1999, and the genomes of many other organisms since then, we already know what genes these organisms have, but we must now study where those genes are used, in which cell types, during which stage of development, and in response to what environmental factors. This ‘epigenetic’ knowledge is crucial to the understanding of development and disease.
Current models in this field can demonstrate that epigenetic information is passed through generations, but they cannot fully explain how the information is inherited. The ChromaPhy project studies the mechanisms of epigenetic inheritance. We combine novel techniques of chemical biology and live-cell imaging with those of molecular genetics, in the model organism Physarum polycephalum. Physarum has a unique ability to absorb whole proteins from its environment into its cellular physiology, making it ideal for our study. ChromaPhy brings together four research groups in Germany and France to support and enable the UK-trained researcher. Because chromatin components are some of the most highly conserved proteins in nature, discoveries we learn from Physarum polycephalum will be directly applicable to human biology.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
- natural sciences biological sciences molecular biology molecular genetics
- natural sciences biological sciences biochemistry biomolecules proteins
- medical and health sciences basic medicine physiology
- natural sciences biological sciences genetics genomes
- natural sciences biological sciences genetics epigenetics
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP7-PEOPLE-2012-IEF
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
80539 MUNCHEN
Germany
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.