Objective TO TEST THE CARCINOGENIC POTENTIAL OF A SERIES OF ASBESTOS AND OTHER FIBROUS MATERIALS. THE PROJECT CONSISTS OF TWO TYPES OF EXPOSURE (INTRA-PLEURAL AND INHALATION) OF ANIMALS TO 10 DIFFERENT SUSPECTED DUSTS. THE DUSTS CONSISTS OF VARIOUS TYPES OF ASBESTOS, A VARIETY OF MAN-MADE MINERAL FIBRES AND SOME NATURALLY OCCURING MINERAL FIBRES. THE DUSTS STUDIED ARE THOSE SUSPECTED OF PRODUCING PLEURAL TUMOURS (MESOTHELIOMA) OR PULMONARY AND/OR PLEURAL FIBROSIS. INTRA-PLEURAL IMPLANTATION IS USED FOR EVIDENCE OF MESOTHELIOMA AND OF PLEURAL FIBROSIS; INHALATION STUDIES ARE USED TO ASSESS FIBROSIS AND TO COMPARE THE INCIDENCE OF BENING AND MALIGNANT PULAMNORY TUMOURS. THE STUDIES ARE CARRIED OUT ON RATS. Programme(s) PRE-ENVPROT 3C - Sectoral research and development programme (EEC) in the field of environment (environmental protection and climatology) - indirect and concerted actions - Environmental protection -, 1981-1985 Topic(s) Data not available Call for proposal Data not available Funding Scheme CSC - Cost-sharing contracts Coordinator Medical Research Council (MRC) EU contribution No data Address 20 Park Crescent W1N 4AL London United Kingdom See on map Total cost No data
