Objetivo Bovine spongiform encephalopathy (BASE), is causing concern for both animal and human health. It was first identified in the United Kingdom in 1986. Sporadic cases have been recognized in, France, Ireland, Switzerland and Oman. The study is to confirm or exclude the suspicion that BSE occurs in other European Community (EC).A diagnostic network for the surveillance of BSE has been set up in the 5 EC States using standard histopathological techniques. In total, 1104 brains from ruminants with neurological disorders have been examined. The distribution of these was 145 in Germany, 245 in Belgium, 398 in Italy, 49 in Luxembourg and 267 in France. So far, the investigation has resulted in the confirmation of the absence of BSE cases in Germany, Belgium, Italy and Luxembourg and the confirmation of five cases of BSE in France. Lesions corresponding to various bovine diseases were seen in the BSE negative cow brains. These diseases included malignant catarrhal fever, listeriosis, bovine vesicular disease, Aujeszky's disease and others.BSE is causing great concern for both animal and human health : in the UK from November 1985 up till 6 December 1991, 42 337 cases were diagnosed in 14 969 farms. The possibility that BSE occurs in other countries has meanwhile been confirmed by 9 cases in Switzerland, 4 cases in France and 2 cases in Oman. Therefore, during two CEC organised training courses at the Central Veterinary Laboratory in Weybridge, one or more researchers per Member State have been trained to use standard histopathological procedures. In five Member States (B, F, D, I and L) where rabies is endemic, brains from cattle with neurological disorders are routinely examined on rabies. The rabies-negative brains are the target samples by excellence to test for BSE. The project will allow to establish a surveillance network for the control of BSE in the five rabies infected Member States. The aim of the project is to confirm or to exclude the suspicion that BSE occurs in these Member States and to have well experienced workers and an elaborated diagnosis infrastructure ready in case of BSE outbreaks in one or more countries. Ámbito científico agricultural sciencesanimal and dairy sciencedomestic animalsanimal husbandrymedical and health sciencesbasic medicineneurology Programa(s) FP2-CAMAR - Research and technological development programme (EEC) in the field of competitiveness of agriculture and management of agricultural resources, 1989-1993 Tema(s) Data not available Convocatoria de propuestas Data not available Régimen de financiación Data not available Coordinador National Instituut voor Diergeneeskundig Onderzoek Aportación de la UE Sin datos Dirección Groeselenberg 99 1180 BRUSSELS Bélgica Ver en el mapa Coste total Sin datos Participantes (6) Ordenar alfabéticamente Ordenar por aportación de la UE Ampliar todo Contraer todo Bundesministerium für Ernährung, Landwirtschaft und Forsten Alemania Aportación de la UE Sin datos Dirección 5300 Bonn Ver en el mapa Coste total Sin datos Centre National d'Études Vétérinaires et Alimentaires (CNEVA) Francia Aportación de la UE Sin datos Dirección 22 rue Pierre Curie 94703 Maisons Alfort Ver en el mapa Coste total Sin datos Dr J. Van Bekkum Países Bajos Aportación de la UE Sin datos Dirección Wildban 8 8222AG LELYSTAD Ver en el mapa Coste total Sin datos Laboratoire de Medecine Veterinaire de l'Etat Luxemburgo Aportación de la UE Sin datos Dirección Av. Gaston Diderich 54 1420 LUXEMBOURG Ver en el mapa Coste total Sin datos Università degli Studi di Torino Italia Aportación de la UE Sin datos Dirección Via Nizza 52 10126 Torino Ver en el mapa Coste total Sin datos École Nationale Vétérinaire de Maisons Alfort Francia Aportación de la UE Sin datos Dirección 7 avenue du Général de Gaulle 94704 Maisons Alfort Ver en el mapa Coste total Sin datos