Objective Objectives: a) Establish a serum bank of seropositive field sera, originating from various regions of the EC, to provide valuable material for validating any future test and also allow examination of different isolates for serotypic variation: collection of serum from animals that have recovered from Porcine Reproductive and Respiratory Syndrom (PRRS), screening for antibody titres in sera of well described breeding and fattering herds. b) Prepare a collection of primary isolates, originating from various regions of the EC. Of the Artiriviridae EAV and SHFV, it is known that various biotypes exist which vary in virulence and in the tendency to cause persistent infection. Therefore, it is important to isolate virus from cases where the method of transmission is unknown. Furthermore, the isolates need to be catalogued and stored under appropriate conditions, including freeze- drying of archive material. c) Study the presence and distribution of Lelystad virus in meat and other pig organs: virus isolation and immuno-histochemical studies on tissue of experimentally infected pigs to investigated the route of infection and the presence of the virus. d) In the future, assuming monoclonal antibody panels become established, hold a workshop to compare reactivities and assemble an EC panel for differentiation. That the virus will ultimately be sequenced, whereupon comparison and exchange of oligonucleoitide primers would prove valuable. Fields of science natural sciencesbiological sciencesmicrobiologyvirologymedical and health scienceshealth sciencespublic healthepidemiology Programme(s) FP3-AIR - Specific research and technological development and demonstration programme (EEC) in the field of agriculture and agro-industry, including fisheries, 1990-1994 Topic(s) 232 - Animal health and well being Call for proposal Data not available Funding Scheme CON - Coordination of research actions Coordinator DLO - CENTRAAL DIERENGENEESKUNDIG INSTITUUT EU contribution No data Address P.O. BOX 365 8200 AJ LELYSTAD Netherlands See on map Total cost No data Participants (6) Sort alphabetically Sort by EU Contribution Expand all Collapse all FRIEDRICH-LOEFLER INSTITUTE FEDERAL RESEARCH INSTITUT FOR ANIMAL HEALTH Germany EU contribution No data Address Boddenblick 5 A 17498 INSEL RIEMS See on map Total cost No data LABORATORIO DE SANIDAD Y PRODUCCION ANIMAL Spain EU contribution No data Address 8001 BARCELONA See on map Total cost No data MAFF Central Veterinary Laboratory United Kingdom EU contribution No data Address Woodham Lane New Haw Addlestone KT15 3NB Weybridge See on map Total cost No data RIJKSUNIVERSITEIT GENT Belgium EU contribution No data Address GENT See on map Total cost No data STATE VETERINARY Denmark EU contribution No data Address KALVEHAVE See on map Total cost No data STATION DE PATHOLOGIE PORCINE France EU contribution No data Address PLOUFRAGEN See on map Total cost No data