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Optical dissection of cortical motor circuits

Objective

"The motor cortex plays a key role in learning and orchestrating fine voluntary movements, which dominate many aspects of our daily lives.
Despite decades of research, considerable controversy remains over the functional organization of this forebrain area and its role in goal directed action. In this project we will combine cutting edge in vivo two-photon imaging, decoding methods and optogenetic manipulations to study different motor related circuits with single cell resolution. This approach will provide us, literally, unprecedented insights into the activity dynamics of large cortical networks during goal directed action. We expect that these experiments in rodents will not only help us understand some of the basic neuronal circuit mechanisms that govern our own actions, but they can potentially pave the way towards more targeted strategies for neuroprosthetic devices."

Call for proposal

ERC-2013-CoG
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Host institution

UNIVERSITE DE GENEVE
EU contribution
€ 1 997 671,00
Address
RUE DU GENERAL DUFOUR 24
1211 Geneve
Switzerland

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Region
Schweiz/Suisse/Svizzera Région lémanique Genève
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Alex Waehry (Dr.)
Principal investigator
Daniel Andreas Huber (Prof.)
Links
Total cost
No data

Beneficiaries (1)