Obiettivo There is an urgent need for improved expansion protocols for haematopoietic stem cells (HSCs). Many studies have tried to stimulate HSC expansion by experimenting with cytokine cocktails in cell culture media. Although these combinations of growth factors are able to increase the amount of HSCs, this happens at the cost of cell maturation: many of the cells in the final culture have lost their 'stemness' and thus their use for treatment and R&D. Dr. Veiga Fernandes has identified crucial survival factors for HSC expansion that increase the stem cell yield 20-fold compared to the current state-of-the-art. This dramatic increase poses serious commercial and societal opportunities. In this ERC PoC project a team of technological and commercial experts will investigate the commercial feasibility of this potentially groundbreaking approach and aims to design the optimal route-to-market with the ultimate goal to attract investors and other strategic partners. Campo scientifico medical and health sciencesmedical biotechnologycells technologiesstem cells Programma(i) FP7-IDEAS-ERC - Specific programme: "Ideas" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013) Argomento(i) ERC-OA-2013-PoC - European Research Council ERC Proof of Concept Invito a presentare proposte ERC-2013-PoC Vedi altri progetti per questo bando Meccanismo di finanziamento CSA-SA(POC) - Supporting action (Proof of Concept) Istituzione ospitante INSTITUTO DE MEDICINA MOLECULAR JOAO LOBO ANTUNES Contributo UE € 149 885,00 Indirizzo AVENIDA PROF EGAS MONIZ 1649 028 Lisboa Portogallo Mostra sulla mappa Regione Continente Área Metropolitana de Lisboa Área Metropolitana de Lisboa Tipo di attività Research Organisations Contatto amministrativo Joana Costa (Dr.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato Beneficiari (1) Classifica in ordine alfabetico Classifica per Contributo UE Espandi tutto Riduci tutto INSTITUTO DE MEDICINA MOLECULAR JOAO LOBO ANTUNES Portogallo Contributo UE € 149 885,00 Indirizzo AVENIDA PROF EGAS MONIZ 1649 028 Lisboa Mostra sulla mappa Regione Continente Área Metropolitana de Lisboa Área Metropolitana de Lisboa Tipo di attività Research Organisations Contatto amministrativo Joana Costa (Dr.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato