Objective
This project aims to reinforce the research excellence of the German Institute of Photonic Technology through knowledge sharing with incoming top-class Australian researcher Dr Stephen Warren-Smith to work in Europe on research in the vibrant field of proteomic sensing.
Proteomics, the study of proteins and their function, is a powerful technique that can be used as a diagnostic tool for various human diseases. Currently, samples must either be extracted from easily accessible fluids such as blood or from invasive biopsy samples. There is an urgent need for techniques that can perform measurements on samples that are difficult to access, such as uterine fluid, without invasive surgery.
We propose to develop highly sensitive micro-interferometers and micro-resonators integrated in optical fibres as miniaturized sensing elements for protein detection in medical applications. This will be achieved by combining sensitive resonance effects, such as a Fabry-Perot interferometer, in conjunction with specific antibodies. Such sensors have already proven successful in physical sensing, such as temperature and strain, and are now in prime position to be extended to the application of biomedical diagnostics. This project will advance these sensors by theoretically and experimentally investigating multi-channel sensors for the purpose of multiplexing biomarkers. This is a critical step for biosensing as it is rare that measuring a single biomarker, without controls, can provide a definitive diagnosis. To demonstrate a specific application the detection of proteomic endometrial biomarkers in difficult to access uterine fluid will be targeted.
This project aims to reach a level of maturity where the biomarkers can be tested in a clinical trial in a subsequent project. This will provide an opportunity for continued engagement between Australia and Germany to address this significant challenge.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences biochemistry biomolecules proteins proteomics
- medical and health sciences clinical medicine surgery
- engineering and technology electrical engineering, electronic engineering, information engineering electronic engineering sensors
- natural sciences physical sciences optics fibre optics
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP7-PEOPLE-2013-IIF
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
07745 Jena
Germany
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.