Objective
The brain is composed of two hemispheres that communicate with each other. While tremendous progress has been made in recent years in understanding the role of each sub brain region, understanding how bilateral communications (BC) contribute to brain computations and behavior is poorly understood. BC is crucial for spatial localization as well as higher cognitive functions such as language and perception of self in humans. Investigating BC has been very difficult to address due to lack of appropriate tools. The recent advance in optogentic, high resolution imaging and multi-unit electrophysiology provides a new opportunity to tackle these questions. In this study I will focus on the BC involved in odor localization as a starting point to understand BC and neural circuits. Understanding odor localization can have an enormous impact on many aspects of our lives such as, pest control, pollution management and plant-insect communications. Furthermore, understanding BC can advance computer science by suggesting new computational approaches that are based on parallelism. We will start by characterizing odor localization ability in mice. Then we will scan for neurons involved in odor localization tasks by recording bilateral neural responses using multi-channel recording in relevant brain regions of behaving mice. To unravel the neural circuits underlying BC in odor localization we will apply imaging techniques to measure the bilateral neural responses of both OB neurons to odors delivered from different directions. We will investigate the role of information exchange between the two OBs by checking the effect of transecting the olfactory communication lines between the two hemispheres on behavior and the neural responses. Using optogentic, we will activate and deactivate particular neurons in one OB of transgenic mice while recording the activity of mirror neurons in the second OB. Our research is aimed to open a new research direction on bilateral brain computations.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
- natural sciences biological sciences neurobiology cognitive neuroscience
- natural sciences computer and information sciences
- natural sciences earth and related environmental sciences environmental sciences pollution
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP7-PEOPLE-2013-CIG
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Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
MC-CIG - Support for training and career development of researcher (CIG)
Coordinator
52900 Ramat Gan
Israel
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.