Objective
Attention deficit hyperactivity disorder (ADHD) is one of the most common and most heritable childhood onset psychiatric conditions. At the same time, genetics of ADHD are largely unknown and increasingly controversial. So far, the genetic risks implicated in ADHD generally tend to have small effect sizes or be rare, or often refer to co-occurring psychopathologies. Thus, there is a growing need for projects pursuing approaches alternative to association studies that have been dominating the field of ADHD genetics in recent years. Motivated by this issue, we propose to examine the epigenetic effects in ADHD. The object is to evaluate imprinting and methylation patterns in ADHD cases and controls. The proposed project aims to utilize methods that complement conventional genetic association studies and have a starting point not limited to hypotheses of specific candidate genes. Imprinting will be analyzed by log-linear regression method, while Illumina Human Methylation 450K chip will be applied to obtain methylation patterns. We will exploit the data of such large cohorts as ALSPAC and Norwegian mother-child study. The assessment of determined epigenetic candidate genes will extend to additional four satellite projects in collaboration with our: (1) clinical group (epigenetics and perinatal factors), (2) neurotargeting group (epigenetics in cell lines), (3) statistical genetics group (epigenome x genome interaction) and (4) animal studies group (epigenetics and stress). The proposal will not only shed light on etiology of ADHD, but also unite several European research groups (Germany, Netherlands, Spain, Norway and UK) as well as create a bridge between the Academia and a private research sector at the University of Bergen (K.G.Jebsen neuropsychiatric center).
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
- medical and health sciences clinical medicine psychiatry
- engineering and technology mechanical engineering vehicle engineering aerospace engineering satellite technology
- natural sciences biological sciences genetics genomes
- natural sciences biological sciences genetics epigenetics
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP7-PEOPLE-2013-CIG
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
MC-CIG - Support for training and career development of researcher (CIG)
Coordinator
5020 Bergen
Norway
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.