Objective
Nano-electromechanical Systems (NEMS) are extremely sensitive detectors of physical parameters. In recent years, the applications of NEMS in mass sensing have gained importance through demonstrations of mass sensitivities at the atomic level and mass measurements of single protein molecules. These demonstrations show that is possible to perform biochemical analysis through NEMS mass measurements (NEMS Mass Spectrometry) especially for physiologically important large molecules and biostructures. The NEMS literature so far has always treated these large molecules as point-particles; however considering the miniaturization trend of NEMS and the significant size of targeted large molecules, this assumption is getting less applicable for experiments. In this project, we demonstrate how we can theoretically and experimentally measure the total mass of an arbitrary mass distribution on NEMS through simultaneous measurements of multiple modes. Furthermore we show that this method can be used to obtain important spatial information about the measured molecule, such as its average position, the variance of its density distribution, the skewness of the molecule etc. This extra characterization modality expands the capabilities of NEMS devices: one can obtain, for instance, the effective density of the sample being measured by combining mass and extent (variance) information. With the proposed technique it is possible to obtain an approximate image of an adsorbed molecule by reconstructing the density profile using the measured moments of the distribution. In the project, multimodal NEMS devices will be fabricated, electronic and vacuum systems to perform the measurements will be constructed and up to the third moment (mass, position, variance and skewness) of different analytes (nanoparticles and biomolecules) will be obtained. The project will be the first step for the development of a novel, powerful NEMS sensing tool and facilitate the integration process of the researcher.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
- natural sciences biological sciences biochemistry biomolecules proteins
- engineering and technology nanotechnology nanoelectromechanical systems
- engineering and technology nanotechnology nano-materials
- natural sciences chemical sciences analytical chemistry mass spectrometry
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP7-PEOPLE-2013-CIG
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Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
MC-CIG - Support for training and career development of researcher (CIG)
Coordinator
06800 Bilkent Ankara
Türkiye
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.