Objective
"There is great need for radically new paradigms that significantly push forward the complexity, multiscale control, and functionality of novel materials. Molecular self-assembling strategies are continuously being explored for developing ever more precise and organized materials. The development of adaptive materials that can be morphed into complex shapes of hierarchical structure through bottom-up mechanisms that mimic those found in tissue development is a fascinating possibility. This proposal (BIOMORPH) aims to develop a novel dynamic self-assembling material fabrication platform that combines the benefits of molecular self-assembly, bioengineering, nanotechnology, and tissue engineering. The system integrates simple peptide and protein building-blocks with multiple cells types to create complex hierarchical, biomimetic, hybrid structures that exhibit remarkable properties such as self-healing and the capacity to undergo morphogenesis. The work would represent a major step-change by developing a dynamic strategy based on emerging physico-chemical mechanisms that generate and dissipate stresses, and maintain a controlled non-equilibrium state that together is reminiscent of elements found in tissue morphogenesis. The work is divided in four work packages that expand from building block design and synthesis to biomechanical and in vitro assessment of the generated materials. The proposed fabrication platform may find applications in a variety of tissue engineering applications. However, as a first stage, the work proposes to grow tubes and tubular networks that recreate vascular tissue."
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
- natural sciences biological sciences biochemistry biomolecules proteins
- engineering and technology nanotechnology
- medical and health sciences medical biotechnology tissue engineering
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP7-PEOPLE-2013-CIG
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
MC-CIG - Support for training and career development of researcher (CIG)
Coordinator
E1 4NS London
United Kingdom
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.