Objective
It is generally agreed that much of variation in gene expression in response to a particular environmental condition has a heritable genetic basis and ultimately, combined with extensive expression variability, it provides the substrate for evolution. Notothenioids, perciform fish living in Antarctic waters, are highly stenotherm organisms and offer a truly unique opportunity to study what characteristics of gene expression levels and pool of expressed genes (the pool of messenger RNAs, mRNA, is called the transcriptome) are behind the differences between stenothems and eurytherms, as a result of the evolution of temperature preference. Studying these fish could help to directly identify the transcriptomic basis of temperature-related evolutionary adaptation by comparing species living in thermally distinct habitats to their most phylogenetically basal relative. In this proposal, three target notothenioid species will be taken into account: two extreme stenotherms adapted to polar conditions, Notothenia rossii and Champsocephalus gunnari and the subpolar eurytherm Eleginops maclovinus. This proposal is aimed at verifying if the evolutionary adaptation to a specific temperature, causes any difference in expression levels at a common set of genes. The modern methodology adopted, the transcriptome sequencing (Illumina RNA-Seq) and the quantitative RT-PCR (OpenArray system) are aimed at collecting and validating a dataset of gene expression rates as broad as possible. Expression of genes hypothetically involved in the temperature adaptation will be also studied in different body tissues, after short and long term exposure to a temperature higher than natural. The likely reduction in available habitats due to global warming and their high specialization to low temperature makes notothenioids hypothetically more vulnerable and potentially genetically compromised in their abilities to acclimate to rising water temperatures and for this reason a hot target for conservation.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP7-PEOPLE-2013-IEF
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
27570 Bremerhaven
Germany
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.