Objective
Over the past century a substantial increase in the incidence of chronic inflammatory diseases has been observed in industrialized countries. This unexpected rise in diseases such as chronic obstructive pulmonary disease (COPD), asthma and inflammatory bowel disease has led to concern about how Western lifestyle may negatively influence our (anti-)inflammatory defense mechanisms. Inflammation is a process that needs to be actively terminated with help of anti-inflammatory and pro-resolving mediators. Several of these mediators are derived from molecules in our environment such as sunlight and nutrition. Accumulating evidence now suggests that Western lifestyle results in a lack of sufficient exposure to sunlight and insufficient intake of particular nutrients due to our diet, resulting in a reduced availability of essential anti-inflammatory and pro-resolving mediators in the body. The work described in this proposal aims to map the role of anti-inflammatory and pro-resolving mediators in smoke-induced inflammation in COPD. The outcomes of this study are expected to contribute to a better understanding of the resolution phase of inflammation and result in the identification of novel therapeutic targets that are applicable for COPD and possibly more inflammatory diseases. Obtaining new insights in the mechanisms underlying resolution of inflammation is of utmost importance to provide a foundation to curb the rise in inflammatory diseases.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- medical and health sciences clinical medicine pneumology asthma
- medical and health sciences health sciences inflammatory diseases
- medical and health sciences clinical medicine gastroenterology inflammatory bowel disease
- medical and health sciences health sciences nutrition
You need to log in or register to use this function
We are sorry... an unexpected error occurred during execution.
You need to be authenticated. Your session might have expired.
Thank you for your feedback. You will soon receive an email to confirm the submission. If you have selected to be notified about the reporting status, you will also be contacted when the reporting status will change.
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP7-PEOPLE-2013-IEF
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
2333 ZA Leiden
Netherlands
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.