Objective
This project aims to restart a research career for the fellow, allowing her to be trained to up-to-date methods in experimental work, genomic tools and data-analysis, capitalizing on her former experience in evolutionary biology. This renewed experience in research is aiming to allow the fellow to move from a current full-time teaching position to research positions.
The research context of the proposal is the interaction between selection levels, in connexion with the broader issue of the emergence of multicellularity. In multicellular organisms, selection can act at the higher level of the whole organism, but also at lower levels, like genes, nuclei, or cells, provided they are genetically heterogeneous. Intra organismal genetic heterogeneity does exist in any individual and may lead to genetic conflicts between selection levels. The best example is cancer, where genetic heterogeneity of some cells leads to the disruption of the whole organism. However, focusing on cheating cell lineages, like cancerous cells, may have lead to overlook that different levels of integration may also act in cooperation rather than generate genetic conflicts.
Fungi, and among them ascomycetes, are ideal models to test for these issues of multilevel selection. Ascomycetes are indeed displaying a high potential for genetic heterogeneity and for nuclear selection, partly because of the dikaryotic phase in their life cycle. We intend to investigate if selection at the nuclear level is acting in cooperation, or conflict, with the organismal level.
We will combine experimental approaches with genomic approaches, using next generation sequencing tools to resolve these issues. The host laboratory has a world-class expertise in these fields. This combination of approaches will be an important output to the mobility of the fellow, allowing her to interact with different groups of her laboratory of origin upon her re-establishment, and contributing to extend the european research network.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences evolutionary biology
- natural sciences biological sciences microbiology mycology
- medical and health sciences clinical medicine oncology
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP7-PEOPLE-2013-IEF
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
751 05 Uppsala
Sweden
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.