Objective
We will investigate the role of the circadian clock in energy balance, metabolism and lifespan of C. elegans.
The evolution of life on Earth has been dominated by the influence of the daily rhythms imposed by its rotational movement. As a consequence, endogenous circadian clocks are present in organisms from all phyla, helping them to anticipate the daily cycles in their environment. This endogenous clock gets information from external cues (zeitgebers) in order to synchronise internal timing to the 24 h day. Circadian clocks regulate processes from gene expression to behaviour, resulting in rhythms in metabolite levels and food intake. The disruption of circadian rhythms has been linked to many pathological conditions, including sleep disorders, depression, metabolic syndrome and cancer. As obesity becomes epidemic in industrialized societies in parallel with a well-documented disruption of our circadian rhythms, the relationship between them becomes highly relevant. We propose to investigate this problem using the nematode C. elegans, an emergent model for the study of circadian rhythms and already established for metabolic research.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
- medical and health sciences clinical medicine psychiatry sleep disorders
- medical and health sciences clinical medicine oncology
- medical and health sciences health sciences nutrition obesity
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP7-PEOPLE-2013-IEF
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Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
41013 Sevilla
Spain
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.