Objective
Single Nano-Particles undergoing Brownian motion in solution colliding at an inert ultramicroelectrode, can serve as nano-electrodes during the time of contact. This provides an entirely new approach to nanoelectrochemistry. Hitherto, this new technique has been used for understanding simple redox reactions. We propose to experimentally study the electron transfer kinetics of single redox active proteins under steady state diffusion conditions, in this elegant configuration. In this way realistic mimicking of electron transfer based natural events will be achieved. In addition, the fundamentals of biological electron transfer will be revisited and re-evaluated. In parallel to this, we plan to use the natural redox activity of selected amino acids within a protein to establish a simple type of biosensor, with approximately attomolar detection sensitivity for label free proteins. Recently, the ability to observe electrocatalytic activity of single NP’s (due to collision with an electrode) was established. In the same way, we plan to use proteins as nanoparticles for biosensing applications. By immobilizing specific aptamers on an inert substrate, the absorption of label free proteins on top of the aptamers will be tracked. Chronoamperometric profiles measured on ultramicroelectrode under potential control should allow detection of attomolar concentrations.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- engineering and technology electrical engineering, electronic engineering, information engineering electronic engineering sensors biosensors
- natural sciences chemical sciences organic chemistry organic reactions
- natural sciences biological sciences biochemistry biomolecules proteins
- engineering and technology nanotechnology nano-materials
- natural sciences chemical sciences organic chemistry amines
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP7-PEOPLE-2013-IEF
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
OX1 2JD Oxford
United Kingdom
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.