Cel "Coral reefs are the world's most diverse marine ecosystems and their existence depends upon a functional intracellular symbiosis between dinoflagellates (single-celled algae) and their coral host. Stresses, such as elevated seawater temperature, cause the obligate symbiosis to break down, a phenomenon known as coral “bleaching”. Incidences of coral bleaching worldwide are on the rise, linked to global climate change. Most corals (phylum Cnidaria) first initiate symbiosis with dinoflagellates (genus Symbiodinium) during larval stages. The molecular basis of coral symbiosis is not well understood, mainly because corals are difficult to work with and have slow generation times. I propose to use an emerging model system based on the small, experimentally tractable sea anemone Aiptasia (phylum Cnidaria) to analyze symbiosis establishment at the cellular and molecular level, including the ways in which symbiosis establishment is affected by environmental changes. First, I will establish a thorough cellular description of symbiosis establishment in Aiptasia larvae. Next, I will identify conserved genes involved in larval symbiosis in cnidarians and use molecular techniques to dissect their functions. Finally, I will establish gain-of function techniques (transgenesis) for Aiptasia using microinjection into early embryos to visualize membranes, nuclei and the cytoskeleton during symbiosis establishment using life imaging. Analysis of coral symbiosis at the cellular and molecular level will provide the missing link between existing genomic approaches and field population-level approaches and will help identify measures to protect coral symbiosis in the face of environmental change." Dziedzina nauki natural sciencesbiological sciencesmicrobiologyphycologynatural sciencesbiological sciencesecologyecosystemsnatural sciencesbiological sciencesbiological behavioural sciencesethologybiological interactionsnatural sciencesearth and related environmental sciencesatmospheric sciencesclimatologyclimatic changesnatural sciencesbiological scienceszoologyinvertebrate zoology Program(-y) FP7-PEOPLE - Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013) Temat(-y) FP7-PEOPLE-2013-CIG - Marie-Curie Action: "Career Integration Grants" Zaproszenie do składania wniosków FP7-PEOPLE-2013-CIG Zobacz inne projekty w ramach tego zaproszenia System finansowania MC-CIG - Support for training and career development of researcher (CIG) Koordynator RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG Wkład UE € 100 000,00 Adres SEMINARSTRASSE 2 69117 Heidelberg Niemcy Zobacz na mapie Region Baden-Württemberg Karlsruhe Heidelberg, Stadtkreis Rodzaj działalności Higher or Secondary Education Establishments Kontakt administracyjny Brigitta Martin Linki Kontakt z organizacją Opens in new window Strona internetowa Opens in new window Koszt całkowity Brak danych
