Objective
Expectations about health and disease induce immune and endocrine responses and directly affect health and treatment outcomes. However, there is an urge to understand the mechanical underpinnings how expectations affect immune and endocrine responses and how this knowledge can be used for therapeutic interventions.
My research group studies the main expectancy learning mechanisms for itch and pain as a generic expectancy model across symptoms and conditions. We recently showed that dual expectancy learning processes (i.e. conditioning and suggestions) are most powerful for itch symptoms, corresponding with findings for other symptoms and conditions. Based on these studies, I propose a groundbreaking dual expectancy learning approach, testing whether combined expectancy learning processes (i.e. both conditioning and suggestions, offered with personalized cues and exposure to relevant stressors) affect most profoundly the immune and endocrine system, in turn affecting health and disease outcomes.
The major aim is to unravel the central mechanisms of how peoples’ expectations affect immune and endocrine responses and related health outcomes, through the use of pioneering multidisciplinary methods in healthy and clinical populations. First, we systematically train immune and endocrine responses and relate them to psychological, neurobiological and genetic mechanisms. Second, we test these manipulations for physical health challenges (e.g. inflammatory or allergic histamine reactions) in healthy subjects and patients. Third, we study the long-term effects in chronic inflammatory itch and pain conditions (e.g. replacing anti-inflammatory pharmacotherapies, reducing side effects).
This interdisciplinary, cross-boundary project progresses key theoretical knowledge of the central expectation mechanisms for immune and endocrine responses. Findings open new horizons for health prevention and therapeutic interventions for various inflammatory conditions and physical symptoms.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
You need to log in or register to use this function
We are sorry... an unexpected error occurred during execution.
You need to be authenticated. Your session might have expired.
Thank you for your feedback. You will soon receive an email to confirm the submission. If you have selected to be notified about the reporting status, you will also be contacted when the reporting status will change.
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
ERC-2013-CoG
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Host institution
2311 EZ Leiden
Netherlands
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.