Service Communautaire d'Information sur la Recherche et le Développement - CORDIS

Statistical multi-Omics UNDerstanding of Patient Samples

De 2015-09-01 à 2018-08-31, projet en cours

Détails concernant le projet

Coût total:

EUR 3 656 977,50

Contribution de l'UE:

EUR 2 953 062,50

Coordonné à/au(x)/en:

Germany

Appel à propositions:

H2020-PHC-2014-two-stageSee other projects for this call

Régime de financement:

RIA - Research and Innovation action

Objectif

Deliverables

Publications

  • GenoGAM: genome-wide generalized additive models for ChIP-Seq analysis
    Author(s): Georg Stricker, Alexander Engelhardt, Daniel Schulz, Matthias Schmid, Achim Tresch, Julien Gagneur
    Published in: Bioinformatics, 2017.  ISSN: 1367-4803
    DOI: 10.1093/bioinformatics/btx150
  • Deficient methylation and formylation of mt-tRNAMet wobble cytosine in a patient carrying mutations in NSUN3
    Author(s): Lindsey Van Haute, Sabine Dietmann, Laura Kremer, Shobbir Hussain, Sarah F. Pearce, Christopher A. Powell, Joanna Rorbach, Rebecca Lantaff, Sandra Blanco, Sascha Sauer, Urania Kotzaeridou, Georg F. Hoffmann, Yasin Memari, Anja Kolb-Kokocinski, Richard Durbin, Johannes A. Mayr, Michaela Frye, Holger Prokisch, Michal Minczuk
    Published in: Nature Communications, issue 7, 2016. Page(s) 12039.  ISSN: 2041-1723
    DOI: 10.1038/ncomms12039
  • Detailed simulation of cancer exome sequencing data reveals differences and common limitations of variant callers
    Author(s): Ariane L. Hofmann, Jonas Behr, Jochen Singer, Jack Kuipers, Christian Beisel, Peter Schraml, Holger Moch, Niko Beerenwinkel
    Published in: BMC Bioinformatics, issue 18/1, 2017.  ISSN: 1471-2105
    DOI: 10.1186/s12859-016-1417-7
  • Unsupervised learning of pharmacokinetic responses
    Author(s): Elson Tomás, Susana Vinga, Alexandra M. Carvalho
    Published in: Computational Statistics, 2017.  ISSN: 0943-4062
    DOI: 10.1007/s00180-016-0707-x
  • Genomic variant annotation workflow for clinical applications
    Author(s): Thomas Thurnherr, Franziska Singer, Daniel J. Stekhoven, Niko Beerenwinkel
    Published in: F1000Research, issue 5, 2016. Page(s) 1963.  ISSN: 2046-1402
    DOI: 10.12688/f1000research.9357.2
  • Mutations in MDH2, Encoding a Krebs Cycle Enzyme, Cause Early-Onset Severe Encephalopathy
    Author(s): Samira Ait-El-Mkadem, Manal Dayem-Quere, Mirjana Gusic, Annabelle Chaussenot, Sylvie Bannwarth, Bérengère François, Emmanuelle C. Genin, Konstantina Fragaki, Catharina L.M. Volker-Touw, Christelle Vasnier, Valérie Serre, Koen L.I. van Gassen, Françoise Lespinasse, Susan Richter, Graeme Eisenhofer, Cécile Rouzier, Fanny Mochel, Anne De Saint-Martin, Marie-Thérèse Abi Warde, Monique G.M. de Sain-van der Velde, Judith J.M. Jans, Jeanne Amiel, Ziga Avsec, Christian Mertes, Tobias B. Haack, Tim Strom, Thomas Meitinger, Penelope E. Bonnen, Robert W. Taylor, Julien Gagneur, Peter M. van Hasselt, Agnès Rötig, Agnès Delahodde, Holger Prokisch, Sabine A. Fuchs, Véronique Paquis-Flucklinger
    Published in: The American Journal of Human Genetics, issue 100/1, 2017. Page(s) 151-159.  ISSN: 0002-9297
    DOI: 10.1016/j.ajhg.2016.11.014
  • DegreeCox – a network-based regularization method for survival analysis
    Author(s): André Veríssimo, Arlindo Limede Oliveira, Marie-France Sagot, Susana Vinga
    Published in: BMC Bioinformatics, issue 17/S16, 2016.  ISSN: 1471-2105
    DOI: 10.1186/s12859-016-1310-4
  • Biallelic IARS Mutations Cause Growth Retardation with Prenatal Onset, Intellectual Disability, Muscular Hypotonia, and Infantile Hepatopathy
    Author(s): Robert Kopajtich, Kei Murayama, Andreas R. Janecke, Tobias B. Haack, Maximilian Breuer, A.S. Knisely, Inga Harting, Toya Ohashi, Yasushi Okazaki, Daisaku Watanabe, Yoshimi Tokuzawa, Urania Kotzaeridou, Stefan Kölker, Sven Sauer, Matthias Carl, Simon Straub, Andreas Entenmann, Elke Gizewski, René G. Feichtinger, Johannes A. Mayr, Karoline Lackner, Tim M. Strom, Thomas Meitinger, Thomas Müller, Akira Ohtake, Georg F. Hoffmann, Holger Prokisch, Christian Staufner
    Published in: The American Journal of Human Genetics, issue 99/2, 2016. Page(s) 414-422.  ISSN: 0002-9297
    DOI: 10.1016/j.ajhg.2016.05.027
  • Genetic diagnosis of Mendelian disorders via RNA sequencing
    Author(s): Laura S Kremer, View ORCID ProfileDaniel M Bader, Christian Mertes, Robert Kopajtich, Garwin Pichler, Arcangela Iuso, Tobias B Haack, Elisabeth Graf, Thomas Schwarzmayr, Caterina Terrile, Eliska Konafikova, Birgit Repp, Gabi Kastenmüller, Jerzy Adamski, Peter Lichtner, Christoph Leonhardt, Benoit Funalot, Alice Donati, Valeria Tiranti, Anne Lombes, Claude Jardel, Dieter Gläser, Robert W Taylor, Daniele Ghezzi, Johannes A Mayr, Agnes Rötig, Peter Freisinger, Felix Distelmaier, Tim M Strom, Thomas Meitinger, Julien Gagneur, Holger Prokisch
    DOI: 10.1101/066738
  • Using R language based bioinformatic workflows as PaaS
    Author(s): Solaimani P., Kallen M., Bertram A.
    Published in: F1000Research, 2016. 
    DOI: 10.7490/f1000research.1113288.1

Coordinateur

EUROPEAN MOLECULAR BIOLOGY LABORATORY
Germany

Contribution de l'UE: EUR 650 403,75


Meyerhofstrasse 1
69117 HEIDELBERG
Germany
Activity type: Private for-profit entities (excluding Higher or Secondary Education Establishments)

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Participants

FRED HUTCHINSON CANCER RESEARCH CENTER NON PROFIT CORPORATION
Fin de participation
United States

Contribution de l'UE: EUR 0


FAIRVIEW AVENUE 1100
98109 SEATTLE WA
United States
Activity type: Research Organisations

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EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZURICH
Switzerland

Contribution de l'UE: EUR 0


Raemistrasse 101
8092 ZUERICH
Switzerland
Activity type: Higher or Secondary Education Establishments

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THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE
United Kingdom

Contribution de l'UE: EUR 323 261,25


TRINITY LANE THE OLD SCHOOLS
CB2 1TN CAMBRIDGE
United Kingdom
Activity type: Higher or Secondary Education Establishments

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LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN
Fin de participation
Germany

Contribution de l'UE: EUR 38 179,45


GESCHWISTER SCHOLL PLATZ 1
80539 MUENCHEN
Germany
Activity type: Higher or Secondary Education Establishments

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INSTITUTO DE ENGENHARIA MECANICA
Portugal

Contribution de l'UE: EUR 315 928,75


RUA ROVISCO PAIS 1
1049001 LISBOA
Portugal
Activity type: Research Organisations

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BEDATADRIVEN BV
Netherlands

Contribution de l'UE: EUR 318 750


BINCKHORSTLAAN 36
2516 S GRAVENHAGE
Netherlands
Activity type: Private for-profit entities (excluding Higher or Secondary Education Establishments)

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UNIVERSITAETSKLINIKUM HEIDELBERG
Fin de participation
Germany

Contribution de l'UE: EUR 0


IM NEUENHEIMER FELD 672
69120 HEIDELBERG
Germany
Activity type: Higher or Secondary Education Establishments

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UNIVERSITAT ZURICH
Switzerland

Contribution de l'UE: EUR 0


RAMISTRASSE 71
8006 ZURICH
Switzerland
Activity type: Higher or Secondary Education Establishments

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Klinikum rechts der Isar - Technische Universitaet Muenchen
Germany

Contribution de l'UE: EUR 331 000


Ismaninger Straße
81675 Muenchen
Germany
Activity type: Higher or Secondary Education Establishments

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TECHNISCHE UNIVERSITAET MUENCHEN
Germany

Contribution de l'UE: EUR 274 570,55


Arcisstrasse 21
80333 MUENCHEN
Germany
Activity type: Higher or Secondary Education Establishments

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HEALTH RESEARCH INC
United States

Contribution de l'UE: EUR 399 593,75


ELM AND CARLTON STREETS
14263 BUFFALO
United States
Activity type: Research Organisations

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Deutsches Krebsforschungszentrum
Germany

Contribution de l'UE: EUR 301 375


Im Neuenheimer Feld 280
69120 HEIDELBERG
Germany
Activity type: Research Organisations

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