Objective
A central discipline of chemistry is the design und creation of molecules with defined structural and chemical properties. Stretching synthetic horizons is a never-ending endeavor to inspirit the chemist’ s creativity in preparing compounds and materials yet to be discovered. Relying on their high strain energy cyclopropanes, as carriers of the most fundamental ring geometry, offer a unique reactivity which allows for a multitude of transformations being grouped in ring-opening reactions, cycloadditions and rearrangements. Major advantage of all these processes is the cyclopropane-derived intrinsic atom-economy.
In this research project, we propose a number of uncommon and challenging reactions making use of donor-acceptor cyclopropanes. Introducing a distinctively controlled bond cleavage we seek to develop novel modes of 1,3-bifunctionalization by σ-bond metathesis, by using hypervalent iodine reagents and by merging organocatalysis with photoredox catalysis. Unprecedented ring-enlargements to four-membered rings by [3+1]-cycloadditions employing isonitriles, carbenes and nitrenes are envisioned, aryne insertions into the three-membered ring leading to indane systems are planned and a general concept for [3+3]-cycloadditions with 1,3-dipoles is presented paving the way to unusual syntheses of heterocycles.
A distinct class of compounds obtainable by our methodology will set the stage to access completely unexplored heterocyclic π-systems being of interest for material science and molecular electronics.
Besides our central goals of advancing organic methodology and to demonstrating the synthetic utility of these novel reactions, we anticipate that mechanistic insights gained by experimental and computational means will be of high impact for the chemistry of this fundamental structural unit in general.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences chemical sciences organic chemistry aldehydes
- natural sciences physical sciences astronomy planetary sciences planets
- natural sciences chemical sciences inorganic chemistry post-transition metals
- natural sciences chemical sciences inorganic chemistry halogens
- natural sciences chemical sciences catalysis
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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H2020-EU.1.1. - EXCELLENT SCIENCE - European Research Council (ERC)
MAIN PROGRAMME
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
ERC-COG - Consolidator Grant
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) ERC-2014-CoG
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
38106 BRAUNSCHWEIG
Germany
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.