Objective
The project is focused the medical device sector and specifically peripheral vascular (PV) devices. A large, unmet, and growing patient population will require treatment for Peripheral arterial disease (PAD) and revenue in this market will continue to grow driven by the aging population and the increased incidence of obesity and diabetes. Percutaneous transluminal angioplasty (PTA) is the most widely used non-surgical treatment, however when used in areas of long calcified stenosis, PTA does not show satisfactory results at long term follow up. Stenting has become the most obvious choice to overcome the limitations of PTA. Unfortunately, long term performance of stents appears to be problematic as they do not prevent (and may to a certain extent even cause) a failure mode known as restenosis. Whilst covered stents have tackled the problem of restenosis within the stent the stent itself interrupts the bloods natural spiral laminar flow (SLF) and increases laterally directed forces and wall shear stress downstream of the implantation causing downstream disease progression. Re-institution of the bloods SLF reduces the forces and turbulence caused by stenting, and reduces neointimal hyperplasia (NIH) distal to the stent which can lead to occlusion distal to the stent.
The global objective of the project is to develop an innovative endovascular stent that will reintroduce the natural spiral laminar flow both through the stent and distal to the stent that can be manufactured to be deployed using standard delivery system profiles. With the long term post project target of increasing patency rates to greater than 80% and reduce restenosis of the stent by greater than 20% and distal stenosis by greater than 20% at 2 year follow up.
As a result of the proposed project, we expect to improve our collective competitiveness and generate increased sales by capturing at least €25M p.a. of the European market for endovascular stents
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- engineering and technology materials engineering colors
- engineering and technology materials engineering coating and films
- social sciences economics and business business and management employment
- medical and health sciences clinical medicine peripheral vascular disease
- natural sciences physical sciences acoustics ultrasound
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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H2020-EU.3.1. - SOCIETAL CHALLENGES - Health, demographic change and well-being
MAIN PROGRAMME
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H2020-EU.3.1.3. - Treating and managing disease
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
SME-1 - SME instrument phase 1
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) H2020-SMEInst-2014-2015
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
DD2 1TY Dundee
United Kingdom
The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.