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Biomarkers of disordered language in autism

Objective

We know talk of ‘the autisms.’ Evidence shows us that autism refers to a heterogeneous group of neurodevelopmental disorders. This heterogeneity has greatly hindered our understanding of autism. This proposal will attempt to disentangle this heterogeneity by focusing on one piece of the autism phenotype: disordered language. More specifically, we will focus on impairments involving phonology, the sounds of language. Infants acquire phonological skills in the first year of life. A disruption in the development of these skills can compromise or even preclude language acquisition. Behavioral studies have provided evidence for an autism subgroup defined by phonological deficits. This subgroup is hypothesized to overlap with specific language impairment (SLI), a developmental language disorder clinically marked by phonological deficits. Given that the presence of speech before age five is the strongest predictor of a better outcome for a child with autism, understanding language deficits that can be present at a very early age is critical. This study will be the first to utilize EEG to examine neural activity relevant to phonological processing in children with autism with and without SLI as well as children with SLI. Our primary goal is to identify biomarkers indexing impaired phonology that can inform earlier diagnoses and treatments for children with disordered language. In addition to this goal, undertaking this research at the BCBL and the University of Seville, which will provide access to both mono- and bilingual children, will enable us to address a critical gap in both autism and SLI research. Developing bilinguals are the rule in the world. Despite this, little is known about bilingualism in autism or SLI. Scientific evidence suggests that there is a ‘bilingual advantage’ that sharpens the mind of bilingual speakers. Could there also be a ‘bilingual advantage’ for children with disordered language? Or is bilingualism simply an extra burden for these children?

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MSCA-IF-EF-ST - Standard EF

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Call for proposal

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(opens in new window) H2020-MSCA-IF-2014

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Coordinator

BCBL BASQUE CENTER ON COGNITION BRAIN AND LANGUAGE
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 170 121,60
Address
PASEO MIKELETEGI 69 2
20009 San Sebastian
Spain

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Region
Noreste País Vasco Gipuzkoa
Activity type
Research Organisations
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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

€ 170 121,60
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