Objective
The main objective of this project is to produce innovative DNA self-assembled nanostructures with the goal of evolving new approaches for drug delivery. The properties of the DNA nanostructures will be tuned by introducing new elements into the nanostructures improving their versatility and structural integrity. This project will aim to:
• build and characterise DNA nanostructures using long oligonucleotides of biological production;
• add different elements to the nanostructures, such as gold nanoparticles and proteins to the nanostructures to tune the respective intrinsic and structural properties;
• develop new strategies to simplify the assessment of the integrity of nanostructures using fluorophores;
• apply the newly developed nanostructures to assemble a delivery system for doxorubicin.
This project will result in a synergy between the applicant’s particular profile and the high quality of the host institution. The applicant has experience in different sets of scientific areas such as fluorescence and nanotechnology as well as a background in molecular and cell biology. Complementarily, the host institution, the Department of Neuroscience at Karolinska Institutet, and Björn Högberg’s laboratory in particular, will provide the necessary knowledge on DNA nanotechnology. Högberg’s group has recently established itself as one of the leading DNA-nanotechnology labs in Europe with high-impact publications in the field.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
- natural sciences biological sciences neurobiology
- natural sciences biological sciences genetics DNA
- natural sciences biological sciences cell biology
- medical and health sciences clinical medicine oncology
- natural sciences biological sciences genetics nucleotides
- natural sciences mathematics pure mathematics geometry
- engineering and technology nanotechnology nano-materials
- natural sciences biological sciences biochemistry biomolecules proteins enzymes
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions
MAIN PROGRAMME
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H2020-EU.1.3.2. - Nurturing excellence by means of cross-border and cross-sector mobility
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
MSCA-IF-EF-ST - Standard EF
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) H2020-MSCA-IF-2014
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
17177 Stockholm
Sweden
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.