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Functional magnetic resonance imaging of the cervical spinal cord at 7 Tesla

Objective

Functional magnetic resonance imaging (fMRI) has become an indispensable tool in neuroscience to study human brain function non-invasively. However, translation of fMRI to investigate function of the second major component of the central nervous system, the spinal cord, has been severely hampered by technical difficulties. Two major challenges for spinal fMRI relate to the anatomy: (i) severe static image distortion caused by vertebrae and the lungs and (ii) dynamic signal instability introduced by breathing. I propose to address these problems by leveraging my expertise with cutting-edge technology for magnetic field compensation, available only to a few sites world-wide including my host institute in Oxford. These advances will enable me to take advantage of the signal-to-noise ratio improvement of ultra-high field (7 Tesla) MRI scanners, which has been clearly demonstrated in the brain but has remained elusive for the spine. The final stage of this project will deploy these methods on a collaborative project investigating the neurobiological mechanisms of pain in the spine. This project will enable me to build strategically on my dual training in engineering and medicine to develop an inter-disciplinary research profile at the interface of neuroscience and methodology.

Fields of science (EuroSciVoc)

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Programme(s)

Multi-annual funding programmes that define the EU’s priorities for research and innovation.

Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

MSCA-IF-EF-ST - Standard EF

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Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

(opens in new window) H2020-MSCA-IF-2014

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Coordinator

THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 183 454,80
Address
WELLINGTON SQUARE UNIVERSITY OFFICES
OX1 2JD Oxford
United Kingdom

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Region
South East (England) Berkshire, Buckinghamshire and Oxfordshire Oxfordshire
Activity type
Higher or Secondary Education Establishments
Links
Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

€ 183 454,80
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