Objective
Despite being the most accessible subcortical auditory structure, little is known about the dorsal cortex (ICd) of the inferior colliculus. Limited physiological evidence hints at functions regarding detection of frequency-modulation, novel sounds and selective attention. This project tries to address three fundamental questions regarding the ICd, namely: (1) what are optimal stimuli for the neurons in the ICd, (2) why is the neuronal activity in ICd important for the organism and (3) how does the neuronal circuit achieve the necessary computation. Taking advantage of state-of-the-art in vivo optical imaging, I will search for effective stimulus features through a population-wide stimulus optimization approach (WP1). The ability to measure neuronal activity over weeks expands the range of sound stimuli researchers can deliver, providing a basis for a more unbiased stimulus search. Moreover, groups of cells that respond to similar features can be detected, while extra efforts can be diverted towards identifying optimal stimuli for the remaining cells. Secondly, a behavioural paradigm will be developed to probe the effect of selective attention on neuronal activity of the ICd (WP2). At the same time, comparing neuronal and behavioural response will help us understand how neuronal representations translate into percept and actions of the animal. Finally, I will investigate how neuronal activities in the ICd are shaped by projections from other brain regions, through the imaging of synaptic terminals from these inputs and, subsequently, optogenetic manipulations. The results will lead to a major understanding in the sensory processing at the auditory midbrain and the functional significance of its interactions with other brain regions. These research outcomes are not ends in themselves, but will provide the Fellow with a basis for further research as an independent group leader.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
- natural sciences biological sciences neurobiology
- medical and health sciences clinical medicine psychiatry
- medical and health sciences basic medicine physiology
- medical and health sciences clinical medicine otorhinolaryngology
- medical and health sciences clinical medicine anaesthesiology
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions
MAIN PROGRAMME
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H2020-EU.1.3.2. - Nurturing excellence by means of cross-border and cross-sector mobility
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
MSCA-IF-EF-ST - Standard EF
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) H2020-MSCA-IF-2014
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
3015 GD Rotterdam
Netherlands
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.