Objective
Phenotypic plasticity, the ability of a genotype to express distinct phenotypes in different environments, is assumed to facilitate individuals coping with new or rapidly changing environments. In the context of climate change, the phenotypic response to temperature has received particular attention since thermal plasticity is affecting the survival of populations and species distribution. Although temperature is an important variable that affects many traits, including gene expression, the genetic basis of phenotypic plasticity evolution remains poorly explored. This project aims at understanding what determines thermal reaction norms, i.e. how gene expression changes with temperature. Preliminary work in the host laboratory suggests that these reaction norms are modified during adaptation of Drosophila melanogaster populations evolving in a new fluctuating thermal environment. Yet, it is unclear whether these changes are the result of selection on phenotypic plasticity or if they are driven by direct selection on the trait value in the novel environments, as both effects are confounded. To detect adaptive change in phenotypic plasticity, we will use a reverse evolution experiment in which D. simulans populations first evolved in one of two different fluctuating thermal environments (hot and cold) and after one year were shifted to the other environment. We will analyse the gene expression profile of these populations at three successive time points during their evolution over a wide range of temperatures (from 15°C to 27°C). By changing the environment in the opposite direction, we will be able to distinguish between selection on plasticity and selection on the trait value, since the latter will not revert plasticity towards the initial state. Hence, we will distinguish adaptive and non-adaptive components of thermal plasticity of gene expression, and identify genetic pathways under selection for phenotypic plasticity.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
- agricultural sciences agriculture, forestry, and fisheries agriculture horticulture fruit growing
- natural sciences biological sciences cell biology
- natural sciences earth and related environmental sciences atmospheric sciences climatology climatic changes
- medical and health sciences basic medicine physiology homeostasis
- natural sciences biological sciences biochemistry biomolecules proteins enzymes
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions
MAIN PROGRAMME
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H2020-EU.1.3.2. - Nurturing excellence by means of cross-border and cross-sector mobility
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
MSCA-IF-EF-ST - Standard EF
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) H2020-MSCA-IF-2014
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
1210 Wien
Austria
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.