Objectif Polycyclic Aromatic Hydrocarbons (PAHs) are major soil pollutants causing special concern due to their high recalcitrance and (geno)toxicity. Despite the extensive knowledge gathered on microbial PAH degradation, current biorestoration technologies are still not sufficiently effective to decontaminate contaminated soils. One of the main characteristics that constrain PAH biodegradability in the environment is their low bioavailability for natural microbial communities, and the concomitant limited degradation rates. In addition, at PAH-polluted sites, other toxicologically relevant polycyclic aromatic compounds (PAC), such as oxygenated PAHs (oxy-PAHs) and nitrogen heterocyclic PAHs (N-PAHs), are generally present, their fate and, in the case of oxy-PAHs, formation being normally neglected. As a result, the success of bioremediation and its ecotoxicological assessment are often limited. NETPAC aims to identify the microbial communities and functions relevant for PAC biodegradation, and their adaptations to low bioavailability conditions, to further exploit them in novel and more sustainable approaches for biologically mediated restoration of PAH-impacted soils. Molecular microbial ecology and analytical chemistry methods in combination with stable isotope tracers will allow a systems biology insight into the complex microbial metabolic networks dealing with PAH-biodegradation and bioavailability in situ, by integrating genomics, transcriptomics and metabolomics data. Diagnostic tools will be developed and applied to monitor a lab-scale Green remediation approach based on enhanced natural attenuation, and to identify the natural microbial adaptations to promote the degradation of the expected low bioavailability residue. Understanding these processes will provide us with tools to assess biodegradation occurrence and, as a final outcome, predict the success of bioremediation thus reducing its uncertainties, one of the main drawbacks of this technology. Champ scientifique natural scienceschemical sciencesanalytical chemistryengineering and technologyenvironmental biotechnologybioremediationnatural sciencesbiological sciencesecologynatural scienceschemical sciencesorganic chemistryhydrocarbonsnatural scienceschemical sciencesorganic chemistryaromatic compounds Programme(s) H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions Main Programme H2020-EU.1.3.2. - Nurturing excellence by means of cross-border and cross-sector mobility Thème(s) MSCA-IF-2014-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) Appel à propositions H2020-MSCA-IF-2014 Voir d’autres projets de cet appel Régime de financement MSCA-IF-GF - Global Fellowships Coordinateur AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS Contribution nette de l'UE € 239 191,20 Adresse CALLE SERRANO 117 28006 Madrid Espagne Voir sur la carte Région Comunidad de Madrid Comunidad de Madrid Madrid Type d’activité Research Organisations Liens Contacter l’organisation Opens in new window Site web Opens in new window Participation aux programmes de R&I de l'UE Opens in new window Réseau de collaboration HORIZON Opens in new window Coût total € 239 191,20 Partenaires (1) Trier par ordre alphabétique Trier par contribution nette de l'UE Tout développer Tout réduire Partenaire Les organisations partenaires contribuent à la mise en œuvre de l’action, mais ne signent pas la convention de subvention. THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL États-Unis Contribution nette de l'UE € 0,00 Adresse "AIRPORT DRIVE 104 SUITE 2200 CB #1350" 27599 Chapel Hill Voir sur la carte Type d’activité Higher or Secondary Education Establishments Liens Contacter l’organisation Opens in new window Site web Opens in new window Participation aux programmes de R&I de l'UE Opens in new window Réseau de collaboration HORIZON Opens in new window Coût total € 160 130,40
