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Biomechancial Aneurysm Risk Assessment Trial

Objective

The formation of aortic aneurysms is the by far the most common aortic disease and its prevalence (1%-5% in the 65+ population) strongly increases with age. Expensive aneurysm repair interventions (about 60k per year in Europe) are performed in order to prevent aortic aneurysms from rupture. However, oversimplified criteria like the maximum transverse aortic diameter or the aortic expansion rate are used to indicate aneurysm repair. These criteria fail to provide patient-specific (individualized) treatment indication, such that many patients are treated without a reason and health care resources are wasted. In contrast VASCOPS’ A4clinics software allows a detailed biomechanical rupture risk assessment, and hence, allows prioritizing patients according to their individual risk of aortic rupture. The market volume for such diagnostic information is estimated to 12000k€ per year in Europe. A4clinics is patented, CE approved and achieved already Technology Readiness Level 9. Despite first retrospective validation studies demonstrated the clinical benefit of the system large prospective validation is needed to fully convince clinicians and to commercially exploit the product. Consequently, the aim of this proposal is to develop a clinical validation plan for the A4clinics software, which is tightly linked to its successful large-scale commercialization. Key points are the definition of a targeted validation strategy and the installation of an effective network of clinical partners, who also should serve as national contact points for product commercialization. In addition early measures to gain awareness of the validation initiative and links to product distribution plans are investigated. The planning will be performed in collaboration with our clinical contact at Karolinska University Hospital in Stockholm, Sweden. Stockholm area screens for aneurysm patients, and, as such provides latest, and for most European countries, a future health care environment.

Fields of science (EuroSciVoc)

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Programme(s)

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Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

SME-1 - SME instrument phase 1

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Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

(opens in new window) H2020-SMEInst-2014-2015

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Coordinator

VASCOPS GMBH
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 50 000,00
Address
PLUEDDEMANNGASSE 39
8010 Graz
Austria

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Südösterreich Steiermark Graz
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

€ 71 429,00
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