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Exploitation of Organic Electrochemical Transistors for Biological Ionsensing – Proof Of Concept

Objective

The IONOSENSE-POC project proposes a novel solution to enable label-free, electronic monitoring of live cells in vitro, using innovative organic bioelectronic technology. The device, the organic electrochemical transistor (OECT), integrated with live cells forming a tissue, has been shown to accurately assess the integrity of the cells, providing dynamic, highly sensitive measurements after exposure to toxins/pathogens. Validation against traditional, optical methods, or commercially available electronic monitoring equipment demonstrated the OECT to have equal or improved sensitivity and temporal resolution. As an added bonus, the OECT is fabricated using conducting polymers, which are not only amenable to low cost processing techniques, but are also optically transparent, yielding devices compatible with high resolution imaging techniques, of critical importance to life scientists. In the POC project, we propose to take this extremely promising technological breakthrough developed in an academic environment, and transition it to a prototype suitable for future commercialization. In parallel, the appropriate steps will be taken necessary to ascertain the market niche(s), initially identified as being in the areas of Biomems targeted for diagnostics/drug discovery. Finally, an adapted exploitation strategy will be developed to best suit the technology developed during the IONOSENSE project. The team assembled to execute the project is extremely committed to the commercialization venture, in particular due to significant feedback from industrial partners (potential endusers) from such diverse biomedical applications as the cosmetics industry, neurotoxicology, electrophysiology instrumentation developers, drug development companies etc. The success of this POC project will have broad ranging, highly positive impacts for society in the EU and further, due to reduction of experimentation on animals, improved healthcare outcomes, and economic development to name a few.

Fields of science (EuroSciVoc)

CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.

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Programme(s)

Multi-annual funding programmes that define the EU’s priorities for research and innovation.

Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

ERC-POC - Proof of Concept Grant

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Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

(opens in new window) ERC-2014-PoC

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Host institution

ASSOCIATION POUR LA RECHERCHE ET LE DEVELOPPEMENT DES METHODES ET PROCESSUS INDUSTRIELS
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 127 755,00
Address
BOULEVARD SAINT MICHEL 60
75272 Paris
France

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Region
Ile-de-France Ile-de-France Paris
Activity type
Research Organisations
Links
Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

€ 149 673,00

Beneficiaries (2)

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