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Industrial Production of Stable Fibroblast Growth Factors for Broad Therapeutic, Research, and Personal Care Applications

Objective

Our business concept focuses on development and marketing of stable fibroblast growth factors (FGFs) for medical, personal care and research use. FGFs are currently being tested therapeutically for use in cancer treatment, regenerative medicine, as well as in cosmetics. The FGF-based therapeutic approaches contribute towards promoting active and healthy ageing, which is a societal challenge common to all European countries. Another important application of FGFs is in the highly attractive cancer stem cell research with the extension to clinical applications. FGFs are being used as an essential reagent ensuring that stem cells are kept in the undifferentiated state. However, FGF instability is one of the major bottlenecks preventing wider use of FGFs. The FGFSTAB project will address this instability by computer-assisted design of multiple stabilizing mutations combined with cutting-edge molecular biology techniques. The expected outcomes of the project will be a universal protein engineering platform for designing stable FGFs and the process for manufacturing of stable FGFs that are not commercially available, even though there is a huge market for them. Added value of our innovation compared to existing solutions will be unprecedented stability, dramatic production cost reductions and the absence of harmful additives. Such FGFs will have much broader applicability than currently used natural molecules. Because of the wide range of products based on FGFs nowadays, we expect that the outcomes of the project will help us to access new high-value markets addressing global societal challenges, such as health care, bio-research, and personal care. All these market segments are characterized by the considerable size, growth and potential impact on people’s everyday lives. The phase 1 of the SME instrument will allow us to carry out well-researched feasibility study which will help us to take our business forward with confidence, and ultimately, increase our bottom line.

Fields of science (EuroSciVoc)

CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.

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Programme(s)

Multi-annual funding programmes that define the EU’s priorities for research and innovation.

Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

SME-1 - SME instrument phase 1

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Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

(opens in new window) H2020-SMEInst-2014-2015

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Coordinator

ENANTIS SRO
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 50 000,00
Address
KAMENICE 771/34
625 00 Brno
Czechia

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Česko Jihovýchod Jihomoravský kraj
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Links
Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

€ 71 429,00
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