SymbioticProject ID: 665046
INNOVATIVE AUTONOMOUS ELECTRICAL BIOSENSOR SYNERGISTICALLY ASSEMBLED INSIDE A PASSIVE DIRECT METHANOL FUEL CELL FOR SCREENING CANCER BIOMARKERS
Biosensors possess recognition elements that bind to target molecules which lead to detectable signals; they are made of two basic components: (i) a bioreceptor or biorecognition element; and (ii) a transducer element. The bioreceptor system interacts with the target analyte and this interaction is monitored by the transducer, which converts the information into a measurable effect such as an electrical, optical or mass-sensitive signal.
This project proposes the development of an autonomous electrochemical biosensor that is lightweight, disposable and low cost by using an outstanding innovative approach: hosting synergistically the bioreceptor element inside a passive direct methanol fuel cell (DMFC). Such approach will provide an electrically independent, very simple, miniaturized, autonomous electrical biosensor. The electrical dependency is eliminated by coupling the biosensor to an electrochemical transducer that is capable of autonomous energy production, the fuel cell. This work proposes a merge between electrical biosensors and fuel cells, combining the advantages of both areas of research in a single synergetic device.
In this envisaged innovative device, the electrical signal obtained from the DMFC is directly related to the concentration of the cancer biomarker in the sample analyzed. The proposed electrochemical biosensor will be completely autonomous operating at room temperature and using the oxygen present in the air, thereby allowing diagnosis everywhere.
Wkład UE: EUR 836 928,75
RUA DR. ANTONIO BERNARDINO DE ALMEIDA 431
Wkład UE: EUR 699 311,25
SOUTH KENSINGTON CAMPUS EXHIBITION ROAD
SW7 2AZ LONDON
Wkład UE: EUR 574 475
CAMPUS DA CAPARICA QUINTA DA TORRE
Wkład UE: EUR 708 313,75
Wkład UE: EUR 527 631,25
NORDRE RINGGADE 1
8000 AARHUS C