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Enantioselective Light-induced Catalysis for Organic Synthesis

Objective

Photochemical reactions are induced by ultraviolet or visible light and they enable the construction of molecular skeletons that are difficult or even impossible to access by any other means. In order to secure a widespread application of these reactions in organic synthesis and in order to make the respective products available for high-tech applications, it is required that photochemical reactions can be performed enantioselectively, i.e. that the three-dimensional architecture of the product molecules is unambiguously defined. Despite some progress in recent years, this challenge has as yet remained unsolved. It is the objective of this proposal to develop catalytic methods that allow the enantioselective synthesis of a broad variety of compound classes by light-induced reactions. The mode of action of potential catalysts is based on energy transfer or on wavelength-selective excitation. In the former scenario, the substrate-catalyst complex will be held together by non-covalent interactions, which position the substrate for an efficient energy transfer and for an enantioselective approach of the reagent. In the latter approach, acid-base interactions in the substrate-catalyst complex will lead to a significant bathochromic absorption shift of the substrate, enabling a selective excitation within the complex and a subsequent enantioselective reaction pathway within a spatially defined chiral environment. Both approaches include the option to employ sunlight as the exclusive energy source to drive enantioselective processes without the need to apply external heat or pressure.

Fields of science (EuroSciVoc)

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Programme(s)

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Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

ERC-ADG - Advanced Grant

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Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

(opens in new window) ERC-2014-ADG

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Host institution

TECHNISCHE UNIVERSITAET MUENCHEN
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 2 357 901,00
Address
Arcisstrasse 21
80333 Muenchen
Germany

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Region
Bayern Oberbayern München, Kreisfreie Stadt
Activity type
Higher or Secondary Education Establishments
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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

€ 2 357 901,00

Beneficiaries (1)

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