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Scale-up of an Advanced Manufacturing process to produce a Pharmaceutical product Application (SAMPA).

Objectif

Sublimity Therapeutics has developed an innovative product, ST-0529, to treat patients with moderate-severe Ulcerative Colitis, a disease that affects 1 million patients in Europe. ST-0529 is enabled using Sublimity Therapeutics ’s proprietary SmPill® nanoemulsion-based technology to target a known and powerful drug, Cyclosporine, directly to inflamed colons. In Phase II human studies, ST-0529 was proven to be effective and safe. ST-0529, an oral product, will compete with injected, expensive drugs that have a risk of serious side effects.

Successful development and commercialisation of ST-0529 will pivot on development of a stable ST-0529 product and a positive outcome of the clinical trials.
Overall, the project will involve leading EU-based specialist SME, technology and equipment suppliers as well as a number of knowledge providers. The budget is €1.6M and will be completed in 58 months.
Successful completion of this project will retain and enhance intellectual property and know-how in Sublimity Therapeutics, increase long term high skill jobs. In parallel, the project will unlock the value inherent not only of ST-0529, but also the underlying SmPill® technology platform. Furthermore, the project will increase the probability of overall company success and increase significantly the NPV to more than €500M.

Appel à propositions

H2020-SMEInst-2014-2015

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Sous appel

H2020-SMEINST-2-2014

Régime de financement

SME-2 - SME instrument phase 2

Coordinateur

SUBLIMITY THERAPEUTICS LIMITED
Contribution nette de l'UE
€ 1 600 000,00
Adresse
INVENT CENTRE DUBLIN CITY UNIVERSITY
9 DUBLIN
Irlande

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PME

L’entreprise s’est définie comme une PME (petite et moyenne entreprise) au moment de la signature de la convention de subvention.

Oui
Région
Ireland Eastern and Midland Dublin
Type d’activité
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Liens
Coût total
€ 2 307 500,00