Objective
One of the most striking demonstrations of experience-dependent neuroplasticity comes from studies of deaf individuals in whom the temporal ‘auditory’ cortex changes its functional tuning to support visual or tactile functions. Age-of-onset and duration of deafness is thought to affect the extent of cross-modal plasticity (CP) in auditory cortex, with earlier onset and longer durations being associated with increased CP. Importantly, previous studies have suggested that the presence of such CP may negatively influence clinical outcomes of cochlear implantation. This has notably resulted in clinicians discouraging parents from teaching sign-language to deaf children for fear that the use of a visual language will promote CP and interfere with the development of auditory abilities, including spoken language, after cochlear implantation. However, recent models have proposed that CP may exert pressure on regions to maintain their cognitive function irrespective of the type of sensory input, and that such maintenance of functional units (e.g. for language) might be positively harnessed in cases of sensory restoration. This is supported by recent research that suggests maintained functional modularity of the visual cortex may be beneficial to the outcome of sight restoration in blind subjects – a finding that will have important implications on the development of guidelines for sight restoration when a technique becomes available. Ironically, the situation is reversed in the deaf, in which guidelines for a widely used technique is based upon limited understanding of the potential benefits of CP and its influence on functional modularity. It is therefore crucial to obtain a more complete picture as to how age-of-onset and duration may affect CP and functional modularity. This project aims to bridge this gap, and specifically seeks to test whether earlier and longer durations of deafness positively correlate with CP and functional modularity in auditory cortex of the deaf.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
- natural sciences biological sciences neurobiology cognitive neuroscience
- humanities languages and literature linguistics sign language
- medical and health sciences clinical medicine surgery
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions
MAIN PROGRAMME
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H2020-EU.1.3.2. - Nurturing excellence by means of cross-border and cross-sector mobility
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
MSCA-IF-EF-RI - RI – Reintegration panel
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) H2020-MSCA-IF-2014
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
NG7 2RD Nottingham
United Kingdom
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.