Objective
When we see an object, hear a sound or smell an odor, precise spatial and temporal patterns of electrical activity are generated within neuronal networks located in specialized brain areas. This electrical representation of the external stimulus mediates perception and sensory experience. However, this process is highly variable, and repetition of the very same sensory experience results in distinct network activity patterns. What does this variability mean for perception? Do distinct activity patterns carry different information about the stimulus? Or rather, does the brain code the same information coming from the outside world in multiple and equivalent ways? Answering these questions and determining how patterns of activity in neuronal populations are used for behavior has not been possible because of the inability to change the activity of neurons with single cell precision over large networks in an intact mammalian brain. In this ambitious proposal we will take a multidisciplinary approach to causally address these questions and decipher the computational principles of brain networks. To achieve this goal we will develop innovative optical technologies for manipulating and monitoring brain circuits with single cell resolution in the intact mouse brain. We will combine these new techniques with novel genetic manipulations and psychophysical behavioral methods that allow precise quantification of animals’ perceptual performance. Using this unique set of tools, we will unravel how the spatial (across neurons) and temporal (across time) aspects of neuronal electrical activity patterns encode information that guides behavior. In achieving our goals we will produce a new technology for stimulating and monitoring neurons in the brains of behaving animals with single-cell specificity that can be adapted to explore cellular dynamics in highly scattering biological media.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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H2020-EU.1.1. - EXCELLENT SCIENCE - European Research Council (ERC)
MAIN PROGRAMME
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
ERC-COG - Consolidator Grant
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) ERC-2014-CoG
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
16163 GENOVA
Italy
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.