Objective
One of the major issues when dealing with therapies for the rehabilitation of the lower limbs in stroke survivors is the in-deep assessment of their effectiveness and the lack of biomarkers for motor recovery. The motor functionality after therapy is evaluated only through clinical tests and scales which do not give information on the effective muscle state and the changes at the corticospinal level. The aim of restoring the motor functions has moved much of the attention of clinicians and researcher towards the use of the combination of brain stimulation techniques for the assessment of cortical excitability and Brain-Computer Interfaces (BCI) for the control of rehabilitation devices. This intervention induces cortical plasticity and reactivates the closed-loop pathway between the impaired cortical tract and the limb by using the cortical command to drive the device for the generation of the afferent volley. However, nothing is known about the changes of the neurophysiological correlates and how these influence the effective recovery of motor functions. NeuroN represents the first systematic attempt to investigate the neurophysiological correlates of changes in the excitability of the cortical areas responsible for ankle dorsiflexion in chronic hemiparetic stroke survivors with drop foot impairment and to identify novel biomarkers of motor recovery. NeuroN aims at filling the gap of knowledge on the functional effects of increased plasticity in chronic stroke survivors by integrating a BCI robot-based platform with the high-density surface electromyographic (HD-sEMG) recordings. The information coming from the decomposition of HD-sEMG signals give insight into the behavior of the motoneurons in the spinal cord and on the effective control command. NeuroN is expected to address one of the most intriguing issues in the neurorehabilitation field: the novel biomarkers developed will help in shaping new therapies for the recovery of motor function of stroke patients.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
- natural sciences biological sciences neurobiology
- natural sciences computer and information sciences software
- medical and health sciences clinical medicine physiotherapy
- medical and health sciences basic medicine neurology stroke
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions
MAIN PROGRAMME
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H2020-EU.1.3.2. - Nurturing excellence by means of cross-border and cross-sector mobility
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
MSCA-IF-EF-ST - Standard EF
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) H2020-MSCA-IF-2014
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
SW7 2AZ LONDON
United Kingdom
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.