Objectif Terrestrial mud volcanos are extreme environments with pH values below even 1, with temperatures up to 70 ºC. They represent ‘hotspots’ of greenhouse gas emissions. Despite the hostile conditions, mud volcanos harbour very unique microbial communities involved in the cycling of elements like carbon, hydrogen, sulfur, and nitrogen. Microbial communities in extreme environments are characterized by low biodiversity and as a consequence serve as good models to study linkages between genomic potential and environmental parameters. Metagenome studies have shown that most of the microorganisms in extreme environments are only distantly related to cultivated bacteria. Therefore, state-of the-art enrichment techniques using chemostat and sequencing batch cultivation with inocula from geothermal sites and driven by physiological information from metagenomic/metatranscriptomic data have a high potential to result in novel isolates. This was already demonstrated by our isolation of both mesophilic and thermophilic acid-loving methanotrophs. The aim of this project is to obtain a fundamental understanding of the microbial ecology of extremely acid terrestrial mud volcanos with special emphasis on the elemental cycles of sulfur, methane and nitrogen. After identification and isolation, the microbial key players will be investigated to unravel the molecular mechanisms by which they adapt to extreme (thermo)acidophilic conditions. To achieve this, several parallel and complementary state-of-the-art-approaches will be combined, e.g. meta-omics, microbial ecophysiology, cultivation techniques, cell biology/biochemistry, metabolism/gene expression studies. The project will profoundly increase the understanding of these natural hotspots of greenhouse gas production/degradation and newly isolated strains have a high potential for finding sustainable solutions for the most pressing grand challenges of the European society e.g. new green enzymatic catalyst and technologies for industry. Champ scientifique natural sciencesbiological sciencesgeneticsDNAnatural sciencesearth and related environmental sciencesgeologyvolcanologynatural sciencesbiological sciencesecologyecosystemsnatural scienceschemical sciencesorganic chemistryaliphatic compoundsnatural sciencesbiological sciencesgeneticsgenomes Programme(s) H2020-EU.1.1. - EXCELLENT SCIENCE - European Research Council (ERC) Main Programme Thème(s) ERC-ADG-2014 - ERC Advanced Grant Appel à propositions ERC-2014-ADG Voir d’autres projets de cet appel Régime de financement ERC-ADG - Advanced Grant Institution d’accueil STICHTING RADBOUD UNIVERSITEIT Contribution nette de l'UE € 2 263 490,00 Adresse HOUTLAAN 4 6525 XZ Nijmegen Pays-Bas Voir sur la carte Région Oost-Nederland Gelderland Arnhem/Nijmegen Type d’activité Higher or Secondary Education Establishments Liens Contacter l’organisation Opens in new window Site web Opens in new window Participation aux programmes de R&I de l'UE Opens in new window Réseau de collaboration HORIZON Opens in new window Coût total € 2 263 490,00 Bénéficiaires (1) Trier par ordre alphabétique Trier par contribution nette de l'UE Tout développer Tout réduire STICHTING RADBOUD UNIVERSITEIT Pays-Bas Contribution nette de l'UE € 2 263 490,00 Adresse HOUTLAAN 4 6525 XZ Nijmegen Voir sur la carte Région Oost-Nederland Gelderland Arnhem/Nijmegen Type d’activité Higher or Secondary Education Establishments Liens Contacter l’organisation Opens in new window Site web Opens in new window Participation aux programmes de R&I de l'UE Opens in new window Réseau de collaboration HORIZON Opens in new window Coût total € 2 263 490,00
