West-LifeProject reference: 675858
Funded under :
World-wide E-infrastructure for structural biology
Total cost:EUR 3 981 125
EU contribution:EUR 3 981 125
Coordinated in:United Kingdom
Call for proposal:H2020-EINFRA-2015-1See other projects for this call
Funding scheme:RIA - Research and Innovation action
The focus of structural biology is shifting from single macromolecules produced by simpler prokaryotic organisms, to the macromolecular machinery of higher organisms, including systems of central relevance for human health. Structural biologists are expert in one or more techniques. They now often need to use complementary techniques in which they are less expert. Instruct supports them in using multiple experimental techniques, and visiting multiple experimental facilities, within a single project.
The Protein Data Bank is a public repository for the final structure. Journals require deposition as a precondition of publication. However, metadata is often incomplete.
This project will pilot an infrastructure for storing and processing data that supports the growing use of combined techniques. There are some technique-specific pipelines for data analysis and structure determination. Little is available in terms of automated pipelines to handle integrated datasets. Integrated management of structural biology data from different techniques is lacking altogether.
The proposed activity will integrate the data management facilities that already exist, and enable the provision of new ones. The resulting integration will provide users with an overview of the experiments performed at the different research infrastructures visited, and links to the different data stores. It will extend existing facilities for processing this data. As processing is performed, it will automatically capture metadata reflecting the history of the project. The effort will use existing metadata standards, and integrate with them new domain-specific metadata terms.
This proposal will develop application level service specific to uses cases in structural biology, enabling structural biologists to get the benefit of the generic services developed by EUDAT and the EGI.
EU contribution: EUR 795 750
Polaris House North Star Avenue
SN2 1SZ SWINDON
EU contribution: EUR 194 625
1066 CX AMSTERDAM
EU contribution: EUR 641 750
EU contribution: EUR 393 250
Zerotinovo namesti 9
60177 BRNO STRED
EU contribution: EUR 402 500
CALLE SERRANO 117
EU contribution: EUR 406 250
PIAZZA SAN MARCO 4
EU contribution: EUR 152 750
UNIVERSITY OF OXFORD OFFICES WELLINGTON SQUARE
OX1 2JD OXFORD
EU contribution: EUR 392 250
3584 CS UTRECHT
EU contribution: EUR 258 000
26 BIS RUE DE LA FONTAINE AU ROI
EU contribution: EUR 344 000
Via Enrico Fermi 40