Objective Given an overwhelming increase of dementia costs and an aging population, there is an urgent need for finding novel therapies for Alzheimer Disease (AD). We are, however, facing a large number of failed clinical trials and a retraction of the nervous system R&D programmes from several big pharmaceutical companies. Increased collaboration between academia and the private sector is required to overcome this challenge.The “Synaptic Dysfunction in Alzheimer Disease” (SyDAD) project will significantly contribute to this approach by training a new generation of researchers with experience and full understanding of the requirements of academia, pharmaceutical companies, the clinics and the society. The research programme will focus on synaptic dysfunction, the main connection point between pathology and cognitive decline in AD. Given the complementary expertise, SyDAD will have excellent opportunities to delineate the cross-talk between different pathways underlying synaptic dysfunction in AD and to identify novel pharmaceutical targets. For future implementation of the research findings into clinical trials, a drug discovery platform will be elaborated, utilising the industrial and clinical expertise in the network. The early-stage researchers (ESRs) will be trained in this environment and provided with a mind-set of future commercial and clinical utilisation of their research findings. Apart from the innovative and collaborative approach of the research programme, the ESRs will also be provided with a training programme where cutting-edge methodology, innovation and transferable skills are key components. The trained ESRs will have excellent intersectoral and interdisciplinary career opportunities and will, together with the SyDAD partners, provide a solid ground to tackle one of the major societal challenges of our century: Finding therapies to decrease the suffering and economic burden of AD patients. Fields of science medical and health sciencesbasic medicinepharmacology and pharmacydrug discoverymedical and health sciencesbasic medicineneurologydementiaalzheimermedical and health sciencesbasic medicinepharmacology and pharmacypharmaceutical drugsnatural sciencesphysical sciencesopticsmicroscopysuper resolution microscopymedical and health sciencesbasic medicinepathology Programme(s) H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions Main Programme H2020-EU.1.3.1. - Fostering new skills by means of excellent initial training of researchers Topic(s) MSCA-ITN-2015-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) Call for proposal H2020-MSCA-ITN-2015 See other projects for this call Funding Scheme MSCA-ITN-ETN - European Training Networks Coordinator KAROLINSKA INSTITUTET Net EU contribution € 1 054 637,28 Address Nobels Vag 5 17177 Stockholm Sweden See on map Region Östra Sverige Stockholm Stockholms län Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 1 054 637,28 Participants (5) Sort alphabetically Sort by Net EU contribution Expand all Collapse all UNIVERSITE DE BORDEAUX France Net EU contribution € 788 626,80 Address PLACE PEY BERLAND 35 33000 Bordeaux See on map Region Nouvelle-Aquitaine Aquitaine Gironde Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 788 626,80 UNIVERSITA DEGLI STUDI DI MILANO Italy Net EU contribution € 774 183,96 Address Via Festa Del Perdono 7 20122 Milano See on map Region Nord-Ovest Lombardia Milano Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 774 183,96 DEUTSCHES ZENTRUM FUR NEURODEGENERATIVE ERKRANKUNGEN EV Germany Net EU contribution € 747 649,44 Address VENUSBERG-CAMPUS 1/99 53127 Bonn See on map Region Nordrhein-Westfalen Köln Bonn, Kreisfreie Stadt Activity type Research Organisations Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 747 649,44 JANSSEN PHARMACEUTICA NV Belgium Net EU contribution € 250 560,00 Address TURNHOUTSEWEG 30 2340 Beerse See on map Region Vlaams Gewest Prov. Antwerpen Arr. Turnhout Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 250 560,00 AXON NEUROSCIENCE SE Slovakia Net EU contribution € 231 078,96 Address DVORAKOVO NABREZIE 10 81102 BRATISLAVA See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region Slovensko Bratislavský kraj Bratislavský kraj Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 231 078,96 Partners (5) Sort alphabetically Sort by Net EU contribution Expand all Collapse all Partner Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement. GOETEBORGS UNIVERSITET Sweden Net EU contribution € 0,00 Address VASAPARKEN 405 30 Goeteborg See on map Region Södra Sverige Västsverige Västra Götalands län Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost No data Partner Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement. ASTRAZENECA AB Sweden Net EU contribution € 0,00 Address Vastra Maelarhamnen 151 85 Sodertaelje See on map Region Östra Sverige Stockholm Stockholms län Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost No data Partner Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement. AlzeCure Discovery AB Sweden Net EU contribution € 0,00 Address KI Science Park, Hälsovägen 7 SE14157 Huddinge See on map Region Östra Sverige Stockholm Stockholms län Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost No data Partner Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement. SERENDIPITY INNOVATIONS AB Sweden Net EU contribution € 0,00 Address STUREPLAN 15 111 45 STOCKHOLM See on map Region Östra Sverige Stockholm Stockholms län Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost No data Partner Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement. ALZHEIMER EUROPE Luxembourg Net EU contribution € 0,00 Address 5 HEIENHAFF 1736 SENNINGERBERG See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region Luxembourg Luxembourg Luxembourg Activity type Research Organisations Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost No data
