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In the eye of the observer: Visual processing at the heart of the retina

Objective

All visual information is broadcasted by an intra-retinal pathway formed by a group of neurons called bipolar cells. They collect photoreceptor signals in the outer retina and relay the signals to the inner retinal neurons. This transfer of visual information is far from passive: Each of the at least 10 bipolar cell types transforms the photoreceptor signals in a unique and highly specific way. As a result, the bipolar cell output signals form the first “elementary operations” from which the neural circuits of the inner retina compose a feature-oriented description of the visual world. Reflecting the partitioning of visual information into parallel channels, the retinal layer in which bipolar cell axon terminals meet their synaptic partners, is highly organized: This so-called “inner plexiform layer” effectively serves as the retina’s “switch board”: The input is provided by the different bipolar cell “channels”, while the output is carried by an even larger number of channels, represented by ganglion cells that form the optic nerve. Each of the ~20 ganglion cell types composes its feature-extracting circuits from a specific set of bipolar cell input it receives. Owing to its regular structure and ease of experimental access, the retina is amongst the best understood self-standing neuronal networks in neuroscience. Indeed, recent advances hold the exciting promise that an in-depth understanding of the bipolar cells – an entire class of neurons – and their role in the first critical steps of visual processing is within reach. Our proposal aims to train young researchers in world-leading research labs towards completing this goal. We will accomplish this by exposing the students to a host of cutting-edge techniques and a broad spectrum of research approaches within the training network – from imaging at synaptic resolution, transgenetics and retina degeneration models to the application of retinal circuit principles for signal processing in artificial vision chips.

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Programme(s)

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Topic(s)

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Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

MSCA-ITN-ETN - European Training Networks

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Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

(opens in new window) H2020-MSCA-ITN-2015

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Coordinator

EBERHARD KARLS UNIVERSITAET TUEBINGEN
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 498 432,90
Address
GESCHWISTER-SCHOLL-PLATZ
72074 Tuebingen
Germany

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Region
Baden-Württemberg Tübingen Tübingen, Landkreis
Activity type
Higher or Secondary Education Establishments
Links
Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

€ 498 432,96

Participants (10)

Partners (4)

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