Objective The aim of this project is to bring together subject matter experts from the academic and non-academic sectors to develop three new categories of quaternary ammonium salts to be used as catalysts for the cost-efficient and green manufacture of high value active pharmaceutical ingredients. In order to achieve this objective the proposal brings together 3 partners with complementary skills:University of Naples(UNIN): experts in the preparation and purification of cyclic peptides. Experts in solid phase synthesis and immobilisation of peptides on solid support.KelAda Pharmachem: Phase transfer catalysis/organo catalysis/scale-up of chemical processesUniversity of Linz(JKU Linz): experts in design of new ammonium salts and optimisation of enantioselective phase transfer catalyses. We have broken this proposal into the following separate Work Packages:WP1. Preparation of new designer ammonium salts [WP leader: Kelada]WP2. Preparation of cyclic peptide based ammonium salts [WP leader: UNINA]WP3. Evaluation of new ammonium salt catalysts prepared through WP1 [WP JKULinz]WP4. Evaluation of new Ammonium salt catalysts prepared through WP2[WP leader: UNINA]WP5. Application of Ammonium salts to drug production [WP leader: Kelada]WP6. Scale up of key steps or the manufacture of drugs [WP leader: Kelada]WP 7. Management, Communication & Dissemination [WP leader: KelAda]The above WP’s will be undertaken via a series of interlinked secondment of researchers between consortium partners and will be complemented by a series of training and other initiatives to facilitate interdisciplinary and intersectoral knowledge sharing and exchange. Fields of science medical and health sciencesbasic medicinepharmacology and pharmacypharmaceutical drugsnatural sciencesbiological sciencesbiochemistrybiomoleculesnatural scienceschemical sciencescatalysis Programme(s) H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions Main Programme H2020-EU.1.3.3. - Stimulating innovation by means of cross-fertilisation of knowledge Topic(s) MSCA-RISE-2015 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) Call for proposal H2020-MSCA-RISE-2015 See other projects for this call Funding Scheme MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) Coordinator UNIVERSITA DEGLI STUDI DI NAPOLI FEDERICO II Net EU contribution € 432 000,00 Address CORSO UMBERTO I, 40 80138 Napoli Italy See on map Region Sud Campania Napoli Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 432 000,00 Participants (2) Sort alphabetically Sort by Net EU contribution Expand all Collapse all KELADA PHARMACHEM LIMITED Ireland Net EU contribution € 180 000,00 Address 161 RATHMINES ROAD LOWER A94 Dublin See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region Ireland Eastern and Midland Dublin Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 180 000,00 UNIVERSITAT LINZ Austria Net EU contribution € 162 000,00 Address ALTENBERGER STRASSE 69 4040 Linz See on map Region Westösterreich Oberösterreich Linz-Wels Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 162 000,00
