Objetivo Extremely low temperatures influence plant development and crop productivity. Therefore, plants have evolved mechanisms to enhance tolerance to freezing (cold acclimation) involving physiological and biochemical modifications. A key side of this process is the biosynthesis and delivery mechanisms of the newly synthesized lipid species towards the appropriate subcellular membranes. Previous studies in Prof Botella´s lab (supervisor) have demonstrated that Arabidopsis SYT1 (Synaptotagmin 1) is an ER-PM (endoplasmic reticulum – plasma membrane) tether component essential for freezing tolerance, and they have characterized SYT3, a novel component of cold-acclimation. The research objective of this proposal is to determine the role that SYT1 and SYT3 have on lipid homeostasis related to cold acclimation at the cellular level, using a combination of mutant analysis, cellular biology, lipidomics and biochemical approaches. Additionally, the findings could have future applications since freezing temperatures are limiting the geographical locations for growing crop plants and periodically account for significant losses in plant productivity in Europe.Dr Ruiz-Lopez (researcher) has wide experience in Plant Lipids. In recent years she has successfully worked in the UK, in one of the world’s leading groups for plant lipids research. Moreover, the host group is one of the world-leading groups in plant responses to abiotic stress research. Their collective expertise represents a very strong team with a proven track-record to conduct world-class research. In addition, secondments are planned to carry out the most advanced lipidomic analysis. This inter-disciplinary Fellowship will exploit the complementary competencies and technologies available at the host to broaden the skills of the researcher, particularly in microscopy, proteomics and management skills, and will also increase the sharing of knowledge and technology transfer between the participant institutions. Ámbito científico natural sciencesbiological sciencesbiochemistrybiomoleculesproteinsproteomicsnatural sciencesbiological sciencesbiochemistrybiomoleculeslipidssocial scienceseconomics and businesseconomicsproduction economicsproductivitynatural sciencesphysical sciencesopticsmicroscopyconfocal microscopymedical and health sciencesbasic medicinephysiologyhomeostasis Programa(s) H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions Main Programme H2020-EU.1.3.2. - Nurturing excellence by means of cross-border and cross-sector mobility Tema(s) MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) Convocatoria de propuestas H2020-MSCA-IF-2014 Consulte otros proyectos de esta convocatoria Régimen de financiación MSCA-IF-EF-ST - Standard EF Coordinador UNIVERSIDAD DE MALAGA Aportación neta de la UEn € 170 121,60 Dirección AVDA CERVANTES, NUM. 2 29016 Malaga España Ver en el mapa Región Sur Andalucía Málaga Tipo de actividad Higher or Secondary Education Establishments Enlaces Contactar con la organización Opens in new window Sitio web Opens in new window Participación en los programas de I+D de la UE Opens in new window Red de colaboración de HORIZON Opens in new window Coste total € 170 121,60
