Objectif With this proposal I plan to dissect, at the genetic level, those circuits controlling goal-oriented movements in mice. In particular, we will focus on the very feature that makes goal-oriented movements so unique in the world of motor control, the spatial awareness of such movements, the fact that their execution is likely to obey a precise metric. I want to understand: (1) which neuronal circuits promote the initiation of targeted-movement and assess the genetic heterogeneity of these circuits. (2) Characterise the function of genetically identified circuit elements during movement execution, with the aim of understanding how the metric of motion is encoded. (3) Investigate how sensory maps and motor maps are aligned during development and probe their plasticity. In prospective (4), we aim to understand how changes in such circuits impinge on the development and evolution of innate behaviours such as predation. The French mathematician Henry Poincaré wrote that ‘The real space is motor space’. Embedded in this idea is the intimate relation between the perceptual encoding of space and motor execution. Accordingly, our research starts at the motor level and aims to move to the perceptual level. Champ scientifique natural sciencesbiological scienceszoologymammalogyprimatologynatural sciencesbiological sciencesgeneticsengineering and technologyelectrical engineering, electronic engineering, information engineeringelectronic engineeringsensorsnatural sciencesbiological sciencesbiological behavioural sciencesethologybiological interactionsnatural sciencescomputer and information sciencesartificial intelligencecomputational intelligence Programme(s) H2020-EU.1.1. - EXCELLENT SCIENCE - European Research Council (ERC) Main Programme Thème(s) ERC-StG-2015 - ERC Starting Grant Appel à propositions ERC-2015-STG Voir d’autres projets de cet appel Régime de financement ERC-STG - Starting Grant Institution d’accueil UNITED KINGDOM RESEARCH AND INNOVATION Contribution nette de l'UE € 1 495 731,00 Adresse POLARIS HOUSE NORTH STAR AVENUE SN2 1FL Swindon Royaume-Uni Voir sur la carte Région South West (England) Gloucestershire, Wiltshire and Bristol/Bath area Swindon Type d’activité Research Organisations Liens Contacter l’organisation Opens in new window Site web Opens in new window Participation aux programmes de R&I de l'UE Opens in new window Réseau de collaboration HORIZON Opens in new window Coût total € 1 495 731,00 Bénéficiaires (1) Trier par ordre alphabétique Trier par contribution nette de l'UE Tout développer Tout réduire UNITED KINGDOM RESEARCH AND INNOVATION Royaume-Uni Contribution nette de l'UE € 1 495 731,00 Adresse POLARIS HOUSE NORTH STAR AVENUE SN2 1FL Swindon Voir sur la carte Région South West (England) Gloucestershire, Wiltshire and Bristol/Bath area Swindon Type d’activité Research Organisations Liens Contacter l’organisation Opens in new window Site web Opens in new window Participation aux programmes de R&I de l'UE Opens in new window Réseau de collaboration HORIZON Opens in new window Coût total € 1 495 731,00